Results 351 to 360 of about 541,956 (367)
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Irreversible inhibitors of serine, cysteine, and threonine proteases.
Chemical Reviews, 2002F. Vinyl Sulfones and Other Michael Acceptors 4683 G. Azodicarboxamides 4695 IV. Acylating Agents 4695 A. Aza-peptides 4695 B. Carbamates 4699 C. Peptidyl Acyl Hydroxamates 4700 D. â-Lactams and Related Inhibitors 4704 E.
J. Powers +3 more
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DEFECTS IN SERINE PROTEASE INHIBITORS [PDF]
Thrombosis and Haemostasis, 1987 Several serine protease inhibitorsof plasma inhibit the activated coagulation enzymes but only antithrombin III(AT-III)and heparin cofactor II (HC-II) are implicated in the pathogenesisof the familial thrombosis. Since thefirst publication (1965) many thrombophilic families with reduced AT-III synthesis have been investigated. These studies have proved
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Flexibility in the specificity site of serine proteases
Biochemistry, 1976The statistical availability of tryptophan and tyrosine residues with one ring face fully exposed to solvent was examined for two serine proteases and their derivatives by investigating the formation of charge transfer (CT) complexes between the aromatic donor residues of the protein and the acceptor 1-methylnicotinamide chloride.
Carol R. Coan +2 more
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Natural Proteinaceous Inhibitors of Serine Proteases
Current Pharmaceutical Design, 2012The deregulated proteolysis is associated with various diseases in humans. Proteases are commonly regarded as the therapeutic targets. Almost one-third of all proteolytic enzymes in humans are serine proteases. This work provides a brief characteristic of the proteinaceous natural inhibitors, mostly of serine proteases.
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ChemInform Abstract: Serine Proteases Inhibiting Cyanopeptides
ChemInform, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Serine proteases regulating synaptic plasticity
Anatomical Science International, 2004A number of molecules have been postulated to be involved in long-term potentiation, an experimental model for learning and short-term memory. Although the molecular mechanisms of the long-term potentiation have been considerably well understood, it is not yet known why and how real memory can last very long with outstanding stability.
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Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
Nature Network Boston, 2010S. Massberg +18 more
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