Results 21 to 30 of about 248,730 (279)
Airborne indoor allergen serine proteases and their contribution to sensitisation and activation of innate immunity in allergic airway disease [PDF]
European Respiratory ReviewCommon airborne allergens (pollen, animal dander and those from fungi and insects) are the main triggers of type I allergic disorder in the respiratory system and are associated with allergic rhinitis, allergic asthma, as well as immunoglobulin E (IgE ...
Xuan Ouyang +3 more
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Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background: In Central and South America, snakebite envenomation is mainly caused by Bothrops spp. snakes, whose venoms feature significant biochemical richness, including serine proteases.
Gloria Maria da Silva +8 more
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REVIEW OF SERINE PROTEASE INHIBITORS: DEVELOPMENT AND APPLICATIONS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2023 A class of enzymes known as proteases is responsible for catalyzing the breakdown of covalent peptide bonds. Proteases account for almost 2% of the genes in humans, infectious organisms, and other forms of life.
Mai Ramadan
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Frontiers in Cellular and Infection Microbiology, 2021 The pathobiont Streptococcus pneumoniae causes life-threatening diseases, including pneumonia, sepsis, meningitis, or non-invasive infections such as otitis media.
Murtadha Q. Ali +4 more
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Novel inhibitors and activity-based probes targeting serine proteases
Frontiers in Chemistry, 2022 Serine proteases play varied and manifold roles in important biological, physiological, and pathological processes. These include viral, bacterial, and parasitic infection, allergic sensitization, tumor invasion, and metastasis. The use of activity-based
Timothy E. G. Ferguson +3 more
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Regulation of Neutrophil Serine Proteases by Intracellular Serpins [PDF]
, 2015 Neutrophil granules contain serine proteases that are central components of the antimicrobial weapons of the innate immune system. Neutrophil proteases also contribute to the amplification and resolution of inflammatory responses through defined ...
Benarafa, Charaf
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Peptidyl Activity-Based Probes for Imaging Serine Proteases
Frontiers in Chemistry, 2021 Proteases catalyze the hydrolysis of peptide bonds. Products of this breakdown mediate signaling in an enormous number of biological processes. Serine proteases constitute the most numerous group of proteases, accounting for 40%, and they are prevalent ...
Paulina Kasperkiewicz
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European Journal of Entomology, 2023 Rhyzopertha dominica is a pest that uses trypsin-like serine protease enzymes to hydrolyse the proteins in the cereal grains on which it feeds. The present study reveals for the first time that that there are both glycosylated and non-glycosylated serine
Fernanda S. ZAVALA-IBARRA +9 more
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Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea. [PDF]
PLoS ONE, 2014 Membrane-bound serine proteases play important roles in different biological processes. Their regulation by endogenous inhibitors is poorly understood.
Nicolas Faller +2 more
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Microbiology Spectrum, 2023 Serine proteases are a group of important hydrolytic enzymes that play vital roles in various cellular processes in fungi. In this study, the S8 serine protease-encoding gene CrKP43 was identified in the highly efficient Clonostachys chloroleuca 67–1 ...
Binna Lv +4 more
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