Results 221 to 230 of about 249,259 (283)

Sequential Design of Activatable Photosensitizers for Ablation of Glioma Cells in Brain Cancer Tissues

Angewandte Chemie, EarlyView.
Gal‐SeNBD‐oleamide is an activatable photosensitizer (PS) with efficient uptake and selective, β‐galactosidase‐triggered activation in cancer cells, enabling efficient photodynamic ablation of glioma cells directly in brain tissue slices from mouse preclinical models and human glioblastoma patients.
Utsa Karmakar, Zhiming Cheng, Andrew D. M. Green, Sam Benson, Eleni Nestoros, Clarissa Lim, Justyna Cholewa‐Waclaw, Fabio de Moliner, Paula Lusarreta, Deborah Seah, Alsadeg Bilal, Neza Alfazema, Thibaud Aymoz‐Bressot, Gillian Morrison, Sonja Vermeren, Steven M. Pollard, Paul M. Brennan, Michael G. Tanner, Marc Vendrell   +18 more
wiley   +2 more sources

Structural Catalytic Core in Subtilisin-like Proteins and Its Comparison to Trypsin-like Serine Proteases and Alpha/Beta-Hydrolases. [PDF]

Int J Mol Sci
Denesyuk AI, Denessiouk K, Johnson MS, Uversky VN.   +3 more
europepmc   +1 more source

<i>Entamoeba histolytica</i>-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities. [PDF]

Front Immunol
Jorge-Rosas F, Díaz-Godínez C, García-Aguirre S, Martínez-Calvillo S, Carrero JC.   +4 more
europepmc   +1 more source

Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target. [PDF]

Eur Respir Rev
Mall MA, Davies JC, Donaldson SH, Jain R, Chalmers JD, Shteinberg M.   +5 more
europepmc   +1 more source

Structural and functional characterisation of isolated puff adder ( B. arietans ) serine proteases

Wilkinson MC, Modahl CM, Saviola A, Tianyi F, Harrison RA, Casewell NR.   +5 more
europepmc   +1 more source

Proteomics of Bacterial and Mouse Extracellular Vesicles Released in the Gastrointestinal Tracts of Nutrient-Stressed Animals Reveals an Interplay Between Microbial Serine Proteases and Mammalian Serine Protease Inhibitors. [PDF]

Int J Mol Sci
Stentz R, Jones E, Gul L, Latousakis D, Parker A, Brion A, Goldson AJ, Gotts K, Carding SR.   +8 more
europepmc   +1 more source

Bacillaceae serine proteases and Streptomyces epsilon-poly-L-lysine synergistically inactivate Caliciviridae by inhibiting RNA genome release. [PDF]

Sci Rep
Yamamoto S, Ogasawara N, Sudo-Yokoyama Y, Sato S, Takata N, Yokota N, Nakano T, Hayashi K, Takasawa A, Endo M, Hinatsu M, Yoshida K, Sato T, Takahashi S, Takano K, Kojima T, Hiraki J, Yokota SI.   +17 more
europepmc   +1 more source

A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation

Angewandte Chemie International Edition, EarlyView.
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf, Mikhail Boym, María Álvarez, Tsvetan Kardashliev, Thomas R. Ward   +4 more
wiley   +1 more source

The Proteolytic Activity of Neutrophil-Derived Serine Proteases Bound to the Cell Surface Arming Lung Epithelial Cells for Viral Defense. [PDF]

Molecules
Assylbekova A, Allayarova M, Konysbekova M, Bekturgan A, Makhanova A, Brown S, Grzegorzek N, Kalbacher H, Kalendar R, Burster T.   +9 more
europepmc   +1 more source

Homology-based identification and structural analysis of <i>Pangasius hypophthalmus</i> Annexins and Serine proteases to search molecules for wound healing applications. [PDF]

Comput Struct Biotechnol J
Avila Rodríguez MI, Velez Rueda AJ, Hernández-Pérez J, Benavides J, Sanchez ML.   +4 more
europepmc   +1 more source