Results 221 to 230 of about 1,481,804 (297)

Education Research: Teaching Neurologic Emergencies Through Serious Games: A Randomized Comparative Intervention Study. [PDF]

open access: yesNeurol Educ
Heidrich M   +6 more
europepmc   +1 more source

Nerandomilast and the Evolving Therapeutic Paradigm in Pulmonary Fibrosis: From Mechanism to Clinical Efficacy

open access: yesiNew Medicine, EarlyView.
Therapeutic mechanism, clinical efficacy and future directions for nerandomilast in pulmonary fibrosis. ABSTRACT The recent Phase III FIBRONEER trials establish nerandomilast, a novel oral phosphodiesterase 4B (PDE4B) inhibitor, as an effective therapy for idiopathic and progressive pulmonary fibrosis. By elevating cyclic adenosine monophosphate (cAMP),
Qianwen Bai   +4 more
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

open access: yesiNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang   +5 more
wiley   +1 more source

Remote Sensing for Irrigation Water Management—The State of the Art and Prospects for Near‐Future Operations

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT A recent UN report describes many regions as facing ‘water bankruptcy,’ a condition in which available water resources can no longer meet existing demands. In practice, this means irrigation will likely bear the greatest burden of future water‐use reductions, a complicated and fraught decision to make given its critical role in food security ...
Wim G. M. Bastiaanssen   +30 more
wiley   +1 more source

Enhancing Reliable Irrigation–Water Supply in Poverty‐Ridden and Drought‐Prone Areas: Pre‐2017 Baseline Evidence From the Tawona Irrigation Scheme, Zimbabwe

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT This study investigates farmers' willingness to pay for a reliable irrigation water supply in Zimbabwe's Tawona irrigation scheme, where intermittent water supply caused by funding shortages threatens irrigation sustainability. Using contingent valuation and logit regression analysis, data were collected from 313 farmers during the 2016/2017 ...
Edgar Muhoyi, Josue Mbonigaba
wiley   +1 more source

Identifying Peer Effects in Networks with Unobserved Effort and Isolated Students

open access: yesJournal of Applied Econometrics, EarlyView.
ABSTRACT Peer influence on effort devoted to some activity is often studied when effort is unobserved, and the researcher instead observes an outcome that combines effort with other shocks. For instance, in education, achievement measures such as GPA reflect both effort and idiosyncratic GPA shocks.
Aristide Houndetoungan   +2 more
wiley   +1 more source

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