Results 161 to 170 of about 258,781 (307)

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Infant and childhood neurodevelopmental outcomes following prenatal exposure to selective serotonin reuptake inhibitors: overview and design of a Finnish Register-Based Study (FinESSI) [PDF]

, 2012
Heli Malm, Miia Artama, Alan S. Brown, Mika Gissler, David Gyllenberg, Susanna Hinkka‐Yli‐Salomäki, Ian W. McKeague, André Sourander   +7 more
openalex   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

An interaction between PAC1 receptor and serotonin 2A receptor involved in receptor trafficking and signal transduction

, 2018
Yusuke Shintani, Atsuko Hayata‐Takano, Naoki Encho, Keita Moriguchi, Hitoshi Hashimoto   +4 more
openalex   +2 more sources

Serotonin‐immunoreactive sensory neurons in the antenna of the cockroach Periplaneta americana [PDF]

, 2013
Hidehiro Watanabe, Miki Shimohigashi, Fumio Yokohari   +2 more
openalex   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, EarlyView.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Serotonin inhibits the influx of iron into cells by decreasing the expression of SLC11A2 in Caco-2 cells. [PDF]

Biomed Rep
Sugino Y, Ameku M, Kawanishi N, Nonen S.
europepmc   +1 more source

Serotonin receptor 2B induces visceral hyperalgesia in rat model and patients with diarrhea-predominant irritable bowel syndrome

Zhengyang Li, Yuqing Mao, Qian Hua, Yonghong Sun, Haiyan Wang, Xuan-Guang Ye, Jing-Xian Hu, Yajie Wang, Miao Jiang   +8 more
openalex   +1 more source

Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands [PDF]

, 2001
Piotr A. Kowalski, Teresa Kowalska, Maria J. Mokrosz, Andrzej J. Bojarski, Sijka Charakchieva‐Minol   +4 more
openalex   +1 more source

Integrating the Gestalt Model of Self With Psychedelic‐Assisted Psychotherapy

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This theoretical integration paper employs a conceptual analysis methodology to synthesize the Gestalt model of self‐as‐process with Psychedelic Somatic Interactional Psychotherapy (PSIP). Unlike traditional psychedelic therapy models that defer therapeutic engagement to postsession integration, PSIP emphasizes an active, directive therapeutic
Travis R. Fox
wiley   +1 more source