Results 171 to 180 of about 275,194 (312)

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Tryptophan's Journey Through Pregnancy: The Role of Serotonin. [PDF]

open access: yesInt J Tryptophan Res
Gendrot B, Vaillancourt C, Fouquet G.
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

ANTIMETABOLITES OF SEROTONIN

open access: yesJournal of Biological Chemistry, 1953
D W, WOOLLEY, E, SHAW
openaire   +2 more sources

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

open access: yesEpilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar   +4 more
wiley   +1 more source

Resumption of Menses and Normalisation of Body Weight in Adolescents Undergoing Specialised Treatment for Anorexia Nervosa Inpatient or Outpatient Treatment

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective To predict resumption of menses (ROM) in patients with anorexia nervosa (AN). Method Females aged 9–17 years with AN, receiving inpatient multimodal treatment (IMT) or family‐based treatment (FBT) underwent assessments at baseline, 6‐month and 12‐month follow‐up (12FU).
Annika Woltmann   +6 more
wiley   +1 more source

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