Results 191 to 200 of about 440,533 (307)

Serotonin's Role in Mental Health Is More Complex than We Thought. [PDF]

ACS Cent Sci
Hlavinka E.
europepmc   +1 more source

An Investigation of Key Symptoms That Account for the Early Response Effect During Psychological Therapy for Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective The early response effect, defined as a reliable symptomatic improvement during the initial phase of treatment, is the most robust predictor of recovery following eating disorder treatment. This study aimed to investigate which symptom domains mostly influence the early response effect. Methods Data from N = 232 adult patients (90.8%
Ammara Imtiaz, Caroline Bell, Glenn Waller, Jaime Delgadillo   +3 more
wiley   +1 more source

Updated Viloxazine Pharmacology: Experiments Establish Norepinephrine Transporter Occupancy and Serotonin 5-HT_2C, 5-HT_2B, and 5-HT₇ Receptor Binding at Therapeutically Relevant Concentrations. [PDF]

Drugs R D
Garcia-Olivares J, Yegla B, Koch J, Yu C, Rubin J.   +4 more
europepmc   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Selective serotonin reuptake inhibitor and serotonin-norepinephrine reuptake inhibitor use and sexual dysfunction: a pharmacovigilance analysis. [PDF]

Sex Med
Shen M, He L, Chen P, Zhang L, Zeng D, Li Y, Li H.   +6 more
europepmc   +1 more source

Influence of Lipid Composition on Nonspecific Interactions of Serotonin with Model Membranes. [PDF]

ACS Pharmacol Transl Sci
Gudyka J, Ceja Vega J, Said J, Silverberg S, Rabadi A, Ceja J, Perla W, Poust C, Andersen E, Mitchell J, Agosti M, Mazzo G, Lee S.   +12 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Inhibitors of Sodium-Dependent Serotonin Transporter Protein (SERT) as Potential New Nematicides. [PDF]

Chem Biodivers
Hodela GJ, de Sousa VP, de Melo MC, Fráguas RM, Terra WC, de Oliveira DF.   +5 more
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

Glycocalyx strengthens endothelial barrier function and protects from angioedema inducing compounds. [PDF]

Front Immunol
Reich A, Lehnert E, Möhrle R, Gierke A, Brunner C, Hoffmann TK, Greve J, Hahn J, Lochbaum R.   +8 more
europepmc   +1 more source