Results 201 to 210 of about 307,503 (301)

Tryptophan metabolism in colorectal cancer: From mechanistic insights to novel therapeutic strategies. [PDF]

Clin Transl Med
Wang R, Shen W, Yang P, Yang D, Cao Y, Zhou Y.   +5 more
europepmc   +1 more source

Adverse Effects of Unsaturated Organic Compounds on Kinetic States During Locomotion Uncovered by Comprehensive Analysis of Behavioral Toxicities in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT Organisms in human living spaces are surrounded by a variety of engineered substances. These chemical compounds have unexpected effects on the environment and human health. In particular, workers in industries face the risk of a health hazard caused by high‐dose or long‐term exposure to chemicals in the workplace.
Masahiro Tomioka
wiley   +1 more source

The microbiota-gut-brain axis in postpartum depression: a review of microbial mechanisms and therapeutic potential. [PDF]

Front Psychiatry
Zhu L, Wang F, Dai Y, Yang X, Wang X.
europepmc   +1 more source

Effects of Glyphosate and Glyphosate‐Based Herbicides on the Mammalian Gut Microbiome: A Critical Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Glyphosate has long been considered to pose negligible direct risk to mammals on the grounds that its molecular target, 5‐enolpyruvylshikimate‐3‐phosphate synthase (EPSPS), of the shikimate pathway, is absent from animal cells. This rationale is inaccurate as a complete toxicological argument, because the shikimate pathway is present in some ...
Robin Mesnage
wiley   +1 more source

The serotonin axis in cancer: metabolism, epigenetics, and immune regulation. [PDF]

Mol Cancer
Zhu J, Bai J, An L, Zhang C.
europepmc   +1 more source

Mental health and healthcare use during COVID‐19 among neurodivergent youth and youth with pre‐existing psychiatric disorders: A systematic review

JCPP Advances, EarlyView.
Abstract Background Neurodivergent youth and youth with pre‐existing psychiatric disorders may have faced additional challenges in navigating the demands and restrictions of the COVID‐19 pandemic. However, less is known about how mental health outcomes and psychiatric healthcare utilization differed across diagnostic groups and other youth‐related ...
Ulyana Sirotina, Bryndis Lara Bjarnadottir, Agnieszka Butwicka, Eivind Ystrom, Jaana Suvisaari, Olli Kiviruusu, Audun Valborgarson, Heiddis Bjork Valdimarsdottir, Helga Ask, Unnur Valdimarsdottir, Thorhildur Halldorsdottir   +10 more
wiley   +1 more source

GSK3 Inhibition During Annelid Head Regeneration Results in a Hyper‐Proliferative Blastema and Impaired Differentiation

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
A whole‐body regenerative annelid was treated with a GSK3 inhibitor. While posterior regeneration was mostly normal, GSK3 inhibition prevented differentiation of anterior‐specific structures and instead produced a persistent, oversized, hyper‐proliferative blastema. This suggests that GSK3 promotes anterior identity and halts proliferation during axial
James D. Nowotny, Eduardo E. Zattara, Maria Balarezo, Kevin G. Nyberg, Kenna M. Costello, Alexandra E. Bely   +5 more
wiley   +1 more source

Gut Microbiota-Driven Neuroimmune Crosstalk in Ulcerative Colitis: From Mechanisms to Therapeutic Implications. [PDF]

Biomedicines
Yu L, He L, Lu Y.
europepmc   +1 more source

A comparative analysis of the prevalence of medicine classes and polypharmacy between community‐dwelling and residential aged care populations in Western Australia

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim, Ninh Ha, David Youens, Rachael Moorin, Andrew Stafford   +4 more
wiley   +1 more source