Results 11 to 20 of about 7,760 (160)

Distribution of Metabotropic Serotonin Receptors in GABAergic and Glutamatergic Neurons in the Auditory Midbrain. [PDF]

J Comp Neurol
The results from this study suggest that the serotonin receptors Htr1a, Htr1b, Htr2a, and Htr2c are largely expressed in the inferior colliculus (IC). Htr1a and Htr1b, which are inhibitory serotonin receptors, are more likely to be expressed by IC glutamatergic neurons.
Galindo KL, Nazir ZA, Silveira MA.
europepmc   +2 more sources

Teratogenic Effects of Serotonin Receptor 2B Disruption on the Migration and Cardiac Derivatives of the Cardiac Neural Crest. [PDF]

Birth Defects Res
ABSTRACT Background Cardiac neural crest cells (cNCCs) are critical for heart development, and their disruption can result in congenital heart defects. Serotonin (5‐HT) signaling, specifically via 5‐HT2B and 5‐HT2C receptors, regulates diverse physiological processes, including neural crest migration.
Wells BK, Garramone GK, Mahomed A, Ezin M.   +3 more
europepmc   +2 more sources

Oppositional effects of serotonin receptors 5-HT1a, 2 and 2c in the regulation of adult hippocampal neurogenesis

Frontiers in Molecular Neuroscience, 2010
Serotonin (5-HT) appears to play a major role in controlling adult hippocampal neurogenesis and thereby it is relevant for theories linking failing adult neurogenesis to the pathogenesis of major depression and the mechanisms of action of antidepressants.
Friederike Klempin, Harish Babu, Davide De Pietri Tonel, Edson Alarcon, Klaus Fabel, Klaus Fabel, Gerd Kempermann, Gerd Kempermann   +7 more
doaj   +1 more source

Central serotonin2C receptor : from physiology to pathology [PDF]

, 2006
Since the 1950s, when serotonin (5-HT) was discovered in the mammalian central nervous system (CNS), an enormous amount of experimental evidence has revealed the pivotal role of this biogenic amine in a number of cognitive and behavioural functions ...
Benigno, Arcangelo, Di Giovanni, Giuseppe, Esposito, Ennio, Matteo, Vincenzo di, Pierucci, Massimo   +4 more
core   +1 more source

Serotonin and motherhood: From molecules to mood [PDF]

, 2019
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming, Lonstein, Joseph S., Pawluski, Jodi L.   +2 more
core   +3 more sources

Serotonin modulation of the basal ganglia circuitry : therapeutic implication for Parkinson’s disease and other motor disorders [PDF]

, 2008
Several recent studies have emphasized a crucial role for the interactions between serotonergic and dopaminergic systems in movement control and the pathophysiology of basal ganglia.
Benigno, Arcangelo, Crescimanno, Giuseppe, Di Giovanni, Giuseppe, Di Matteo, Vincenzo, Esposito, Ennio, Pierucci, Massimo   +5 more
core   +1 more source

Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775) [PDF]

, 2018
Lysergic acid diethylamide (LSD) is perhaps one of the best-known psychoactive substances and many structural modifications of this prototypical lysergamide have been investigated. Several lysergamides were recently encountered as “research chemicals” or
Abramson, Abramson, Araneda, Ashby, Babij, Blair, Brandt, Brandt, Brandt, Brandt, Canal, Chemel, Darmani, Darmani, Darmani, Dilly, Dursun, Forster, Fox, Gasser, Gerber, Gogerty, González-Maeso, Gudelsky, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Heal, Hintzen, Hoffman, Hofmann, Isbell, Karst, Kim, Kleven, Kraehenmann, Krebs-Thomson, Li, Marona-Lewicka, Martel, Matsumoto, Nakahara, Newman-Tancredi, Nichols, Nichols, Nichols, Nichols, Pokorny, Preller, Rényi, Salmi, Schreiber, Serafine, Sheldrick, Sheldrick, Silva, Stoll, Strassman, Testa, Valle, Vetulani, Vickers, Vollenweider, Wacker, Watts   +67 more
core   +1 more source

N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT₂Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues [PDF]

ACS Chemical Neuroscience, 2015
A series of N-benzylated-5-methoxytryptamine analogues was prepared and investigated, with special emphasis on substituents in the meta position of the benzyl group. A parallel series of several N-benzylated analogues of 2,5-dimethoxy-4-iodophenethylamine (2C-I) also was included for comparison of the two major templates (i.e., tryptamine and ...
Nichols, DE, Sassano, MF, Halberstadt, AL, Klein, LM, Brandt, SD, Elliott, SP, Fiedler, WJ   +6 more
openaire   +2 more sources

Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy : the missing link? [PDF]

, 2015
5-Hydroxytryptamine 2A receptors (5-HT2A-Rs) are G-protein coupled receptors. In agreement with their location in the brain, they have been implicated not only in various central physiological functions including memory, sleep, nociception, eating and ...
Di Giovanni, Giuseppe, Guiard, Bruno P.
core   +1 more source

Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens [PDF]

, 2016
The present study investigated interactions between the novel psychoactive tryptamines DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and transporters compared with the classic hallucinogens lysergic acid diethylamide (LSD ...
Hoener, Marius C., Liechti, Matthias E., Moning, Olivier D., Rickli, Anna   +3 more
core   +1 more source