Results 101 to 110 of about 25,888 (267)

Clinically important drug interactions with opioid and non-opioid analgesics [PDF]

Arhiv za farmaciju, 2019
Patients often seek advise from doctors and pharmacists about pain treatment. Opioid and non-opioid analgesics are the most commonly used drugs in the treatment of pain, but they have potential for pharmacodynamic and pharmacokinetic drug-drug ...
Vezmar-Kovačević Sandra, Vučićević Katarina, Topić-Vučenović Valentina, Rajkovača Zvezdana, Miljković Branislava   +4 more
doaj  

Multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain

Molecular Pain, 2018
Vortioxetine is a multimodal antidepressant that potently antagonizes 5-HT3 serotonin receptors, inhibits the high-affinity serotonin transporter, activates 5-HT1A and 5-HT1B receptors, and antagonizes 5-HT1D and 5-HT7 receptors.
Anna Rita Zuena, Daniela Maftei, Giovanni Sebastiano Alemà, Francesca Dal Moro, Roberta Lattanzi, Paola Casolini, Ferdinando Nicoletti   +6 more
doaj   +1 more source

From acute to chronic pain: tapentadol in the progressive stages of this disease entity [PDF]

, 2017
OBJECTIVE: Chronic pain is now recognized as a neural disease, which results from a maladaptive functional and structural transformation process occurring over time. In its chronic phase, pain is not just a symptom but also a disease entity.
Coluzzi, Flaminia, Fornasari, D, Pergolizzi, J, Romualdi, P.   +3 more
core  

Poisoning with illicit substances: toxicology for the anaesthetist [PDF]

, 2013
The consumption of illicit substances represents a considerable threat to the health and wellbeing of particular sectors of our communities. Hospitalisation is sometimes required for the treatment of the direct toxic effects of the drugs as well as for ...
Irwin, MG, Wong, GTC
core   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Characteristics of patients with anxiety disorder without selective serotonin reuptake inhibitor prescription over a two‐year period of pharmacotherapy

Neuropsychopharmacology Reports
Introduction Pharmacotherapy such as selective serotonin reuptake inhibitors (SSRIs) or serotonin‐noradrenaline reuptake inhibitors is recommended for the treatment of anxiety disorders.
Keisuke Mori, Fumitoshi Kodaka, Arisa Yamamoto, Ryuichi Yamazaki, Junpei Ishii, Wataru Yamadera, Hisatsugu Miyata, Masahiro Shigeta   +7 more
doaj   +1 more source

Current Developments in the Treatment of Postpartum Depression: Zuranolone

Eurasian Journal of Medicine
Pregnancy is a period in a woman’s life during which she experiences physiological, psychological, and social changes. These changes can lead to various mental illnesses, including postpartum depression (PPD), which is common during the perinatal period.
Dogancan Sonmez, Cicek Hocaoglu
doaj   +1 more source

Psychomotor depressive symptoms may differentially respond to venlafaxine

, 2013
Predicting differential antidepressant efficacy remains an elusive goal in major depressive disorder (MDD). The aims of this study were three-fold. Firstly, to examine if psychomotor retardation symptoms (item 8 on the 17-item Hamilton Depression Rating ...
Berk, Michael, Bousman, Chad A., Byron, Keith, Ng, Chee H., Singh, Ajeet B.   +4 more
core   +1 more source

Potential drug therapies for the treatment of fibromyalgia [PDF]

, 2016
INTRODUCTION: Fibromyalgia (FM) is a common, complex chronic widespread pain condition is characterized by fatigue, sleep disturbance and cognitive dysfunction.
Lawson, Kim
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source