Results 111 to 120 of about 25,888 (267)

From Serotonin to Neuroplasticity: Evolvement of Theories for Major Depressive Disorder

Frontiers in Cellular Neuroscience, 2017
The serotonin (5-HT) hypothesis of depression has played an important role in the history of psychiatry, yet it has also been criticized for the delayed onset and inadequate efficacy of selective serotonin reuptake inhibitors (SSRIs).
Bangshan Liu, Jin Liu, Mi Wang, Yan Zhang, Lingjiang Li   +4 more
doaj   +1 more source

Selective Serotonin Reuptake Inhibitor Antidepressant Treatment Discontinuation Syndrome: A Review of the Clinical Evidence and the Possible Mechanisms Involved [PDF]

, 2013
Besides demonstrated efficacy, selective serotonin reuptake inhibitors (SSRIs) hold other advantages over earlier antidepressants such as greater tolerability and a wider range of clinical applications.
Thibault Renoir
core   +2 more sources

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Suicidality during treatment with serotonin and norepinephrine reuptake inhibitors

European Psychiatry
Introduction Treatment choice when prescribing antidepressants for major depressive disorder (MDD) is often influenced by safety and tolerability profiles.
I. Da Fonseca Pinto, A. Elias de Sousa, M. A. Vieira-Coelho   +2 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Monoamine reuptake inhibition and mood-enhancing potential of a specified oregano extract [PDF]

, 2017
A healthy, balanced diet is essential for both physical and mental well-being. Such a diet must include an adequate intake of micronutrients, essential fatty acids, amino acids and antioxidants.
Aston, James, Colletto, Biagio, Elliott, J. Martin, Etheve, Stéphane, Fowler, Ann, Goralczyk, Regina, Kilpert, Claus, Mechan, Annis O., Mohajeri, M. Hasan, Rieger, Henry, Schüler, Göde, Seifert, Nicole, Wyss, Adrian, Wöhrle, Tina   +13 more
core  

Management of Widespread Pain and Fibromyalgia [PDF]

, 2016
Peer reviewedPublisher ...
Basu, Neil, Dean, Linda E, Whibley, Daniel   +2 more
core   +2 more sources

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Noticeable changes in diaphoresis severity following pain management medication adjustments in a complex regional pain syndrome patient [PDF]

Anesthesia and Pain Medicine
Background Serotonin syndrome results from the use of serotonergic agents that elevate intrasynaptic serotonin level or excessively activate serotonin postsynaptic receptors.
Joon Hee Lee, Eun Joo Choi, Pyung-Bok Lee   +2 more
doaj   +1 more source

Selective Serotonin/Noradrenaline Reuptake Inhibitors (SNRIs)

CNS Drugs, 1995
Peer ...
openaire   +2 more sources