Results 171 to 180 of about 77,943 (311)

Effects of frequently used psychiatric drugs on subjective dry mouth, salivary secretion and DMFT in outpatients. [PDF]

BMC Oral Health
Kovács A, Károlyházy K, Tolna J, Gótai L, Demeter T, Kerémi B, Vág J, Márton K.   +7 more
europepmc   +1 more source

Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors

Acta Crystallographica Section F, EarlyView.
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima, Chiemi Mishima-Tsumagari, Mayumi Sakata-Sakuta, Ryo Iwaoka, Kunihiko Iwamoto   +4 more
wiley   +1 more source

Drug-Induced Osteoporosis. [PDF]

J Clin Med
Gasser RW, Kocijan R, Zendeli A, Resch H.   +3 more
europepmc   +1 more source

Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression: A Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the effects of Clinical Pilates (CP) training and aerobic exercise (AE) on menopausal symptoms, depressive symptoms, quality of life (QoL), and sleep quality in postmenopausal women. Design Parallel‐group randomised controlled trial. Setting A Healthy Life Center in Bitlis, Turkey.
Başak Can, Serkan Usgu, Günseli Usgu
wiley   +1 more source

Palonosetron, a 5-HT3 Receptor Antagonist, Induces G1 Cell Cycle Arrest and Autophagy in Gastric Cancer Cells. [PDF]

Int J Mol Sci
Yoo YC, Lin L, Lee S, Shin YR, Oh JE, Kim NY.   +5 more
europepmc   +1 more source

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Tribute to Alberto J. Kaumann. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Christ T, Ravens U.
europepmc   +1 more source

Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang, Kathryn Halliday, Deborah Allen, Wema Meranda Mtika, Eve Tranter, Grace Glover, Lynn Tatnell, Julia Hippisley‐Cox, Carol Coupland, Sarah Hillman, Jennifer Hirst   +10 more
wiley   +1 more source

Neural signaling mechanisms in depression: bridging classical monoamine hypotheses, animal models, and emerging antidepressant strategies. [PDF]

Front Cell Dev Biol
Yamamoto M, Hirakata H, Toda K.
europepmc   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source