Results 131 to 140 of about 143,694 (316)

Efeitos das injeções de agonistas e antagonistas gabaérgicos e agonistas serotonérgicos na concha do núcleo accumbens sobre comportamentos defensivos e ingestivos em ratos [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasA fim de estabelecer uma relacao funcional entre o controle dos comportamentos defensivos e ingestivos em ratos, esse ...
Lopes, Ana Paula Fraga
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Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

British Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus, Pauline Schiro, Jean‐Luc Faillie, Romane Freppel, Johana Béné, Claire de Canecaude, François Montastruc   +6 more
wiley   +1 more source

Role of prucalopride, a serotonin (5-HT4) receptor agonist, for the treatment of chronic constipation

, 2010
Banny S Wong, Noriaki Manabe, Michael CamilleriClinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Mayo Clinic, Rochester, Minnesota, USAAbstract: Constipation affects up to a quarter of the population in developed ...
Michael Camilleri, Banny S Wong, Noriaki Manabe   +2 more
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Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Caracterização da contração induzida por serotonina em corpo cavernoso de rato: Luigi Marins Berretta ; orientadora, Áurea Elizabeth Linder [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A disfunção erétil pode ser definida como a dificuldade parcial ou total de se obter e/ou ...
Berretta, Luigi Marins
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Distribution of cells responsive to 5-HT6 receptor antagonist-induced hypophagia

, 2014
Open Access funded by Medical Research CouncilPeer ...
Shaw, Jill, Heisler, Lora K., Evans, Mark L, Burke, Luke K., Evans, Mark L., Garfield, Alastair S., Garfield, Alastair S, Burke, Luke K, Heisler, Lora K   +8 more
core   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Efeitos do bloqueio de receptores a1 do núcleo mediano da rafe sobre o comportamento alimentar e expressão da proteína Fos [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas, Florianópolis, 2014A serotonina (5HT) é um neurotransmissor envolvido no controle da ingestão de ...
Silva, Eduardo Simão da
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From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source