Results 161 to 170 of about 143,694 (316)

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Benzazepines Derivatives: Synthetic Strategy, Structural-Activity Relationships, and Medical Potential as Dopamine and Serotonin Receptor Modulators. [PDF]

ACS Omega
Verma SS, Verma A, Verma SK, Hasan SM, Verma L, Anas M.   +5 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Allosteric activation of the glutamate receptor mGlu2 by the serotonin receptor 5-HT_2A. [PDF]

Nat Commun
Gai S, Lin L, Meng J, Wu Y, Xue L, Xu C, Sun Q, Ricarte A, Dalton J, Renault P, Giraldo J, Pin JP, Rondard P, Liu J.   +13 more
europepmc   +1 more source

2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery. [PDF]

J Med Chem, 2023
Bender AM, Parr LC, Livingston WB, Lindsley CW, Merryman WD.   +4 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

SERAAK2 as a Serotonin Receptor Ligand: Structural and Pharmacological In Vitro and In Vivo Evaluation. [PDF]

Molecules
Kaczor AA, Zięba A, Karcz T, Jastrzębski MK, Szczepańska K, Laitinen T, Castro M, Kędzierska E.   +7 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model. [PDF]

Sci Rep
Du Y, Miller VK, Mellies AJ, Broadie K.
europepmc   +1 more source

Serotonin receptor [PDF]

Science-Business eXchange, 2011
openaire   +1 more source