Results 181 to 190 of about 143,694 (316)

Imidazoles as Serotonin Receptor Modulators for Treatment of Depression: Structural Insights and Structure-Activity Relationship Studies. [PDF]

Pharmaceutics, 2023
Goel KK, Thapliyal S, Kharb R, Joshi G, Negi A, Kumar B.   +5 more
europepmc   +1 more source

The impact of exercise on cognitive function and brain health across the lifespan: A systematic review

Ibrain, EarlyView.
This systematic review of 37 studies demonstrates that aerobic, resistance, and combined exercise enhance cognitive function and brain health across all ages. Exercise promotes neuroplasticity, upregulates brain‐derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF), and mitigates age‐related cognitive decline, establishing ...
Issam AbuQeis, Abeer Teeti, Amro Titi
wiley   +1 more source

Limb Compression Therapy and Chemotherapy‐Induced Peripheral Neuropathy in Women With Gynecologic Cancers: A Prospective Self‐Controlled Study(NEURO‐GLOVE Trial)

International Journal of Cancer, EarlyView.
With no effective drug‐based prevention strategies available for chemotherapy‐induced peripheral neuropathy (CIPN), research in neuroprotective approaches has grown. Of particular interest is mechanical compression, which may protect nerves by temporarily reducing blood flow during treatment. The authors here conducted a prospective trial in women with
Kadriye Başkurt, Galip Can Uyar, Enes Yeşilbaş, Fatma Zehra Altunç, Damla Erimhan Çevik, İsmet Murat Melek, Yasemin Eren, Ömür Berna Çakmak Öksüzoğlu, Kadriye Bir Yücel, Antonio Di Meglio, Isabelle Ray‐Coquard, Osman Sütcüoğlu   +11 more
wiley   +1 more source

Serotonin receptor 5-HT_2A as a potential target for HCC immunotherapy. [PDF]

J Immunother Cancer
Tay RE, Ho CM, Ang NDZ, Tay HC, Lopez DZ, Na QR, Tan YW, Koh SM, Tan KP, Lee W, Lim J, Lau M, Toh HC, Rotzschke O, Rénia L.   +14 more
europepmc   +1 more source

The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition. [PDF]

Front Oncol, 2023
Vanneste M, Venzke A, Guin S, Fuller AJ, Jezewski AJ, Beattie SR, Krysan DJ, Meyers MJ, Henry MD.   +8 more
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source

Teratogenic Effects of Serotonin Receptor 2B Disruption on the Migration and Cardiac Derivatives of the Cardiac Neural Crest. [PDF]

Birth Defects Res
Wells BK, Garramone GK, Mahomed A, Ezin M.   +3 more
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Impact of specific serotonin receptor modulation on restricted repetitive behaviors. [PDF]

Front Behav Neurosci, 2022
Alvarez BD, Cavazos C, Morales CA, M Lopez S, Amodeo DA.   +4 more
europepmc   +1 more source