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Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists. [PDF]

open access: yesACS Med Chem Lett
Jayakodiarachchi N   +9 more
europepmc   +1 more source
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Tryptamine and Serotonin Receptors

Nature, 1962
A RECENT communication by Vane et al. entitled “Tryptamine Receptors in the Central Nervous System”1 concluded, on the basis of indirect evidence, that the receptors for tryptamine and for serotonin (5-hydroxytryptamine) were the same. Because the authors neglected to mention some earlier evidence of a more direct kind which showed clearly that certain
D W, WOOLLEY, E, SHAW
openaire   +2 more sources

Palmitoylation of serotonin receptors

Biochemical Society Transactions, 2013
The covalent attachment of palmitic acid to one or more cysteine residues (S-palmitoylation) is a widespread modification of signalling proteins. With the finding that palmitoylation is a dynamic process, it is now widely accepted that repeated cycles of palmitoylation/depalmitoylation could be involved in the regulation of multiple signalling ...
Nataliya, Gorinski, Evgeni, Ponimaskin
openaire   +2 more sources

Serotonin Transporter and Serotonin Receptors

2013
The nature of the primary defect responsible for triggering and maintaining pulmonary artery smooth muscle (PA-SMC) proliferation in pulmonary artery hypertension (PAH) is poorly understood but may be either an inherent characteristic of PA-SMCs or a secondary response to an external abnormality, such as upregulation of growth factors.
Serge, Adnot   +4 more
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Subtypes of Receptors for Serotonin

Annual Review of Pharmacology and Toxicology, 1990
Interest in the physiological functions of 5-hydroxytryptamine (5-HT; seroto­ nin) has increased steadily since its discovery in the intestine (1) and in serum (2). Its identification in brain in the early 1950s (3), followed a decade later by the initial studies of its distribution in brain by histofluorescence (4), stimulated investigations of the ...
A, Frazer, S, Maayani, B B, Wolfe
openaire   +2 more sources

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