Results 171 to 180 of about 40,021 (309)

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HT<sub>1</sub> Receptor Agonists in Awake Mice. [PDF]

open access: yesPharmacol Res Perspect
Brems BM   +5 more
europepmc   +1 more source

The Role of Opioids on Motor Activity in Physio-pathological Conditions

open access: yes, 2009
To date, four principal classes of opioid peptide receptors, μ (MOP), κ (KOP), δ (DOP) and ORL- 1 (NOP) have been identified and cloned. The experimental and clinical importance of this receptor family has been amply demonstrated in many diseases ...
Mabrouk, Omar Sharif
core  

Weight‐Lowering Drugs and Natural Female Fertility—A Systematic Review and Meta‐Analysis

open access: yesClinical Obesity, Volume 16, Issue 4, August 2026.
ABSTRACT Overweight and obesity are global health concerns linked to impaired female fertility. Weight‐lowering drugs are an alternative for achieving weight loss; however, their effect on natural female fertility is unclear. A systematic review and meta‐analysis were conducted to summarise the literature on the effects of weight‐lowering drugs on ...
Shaikha Jabor Alnaimi   +4 more
wiley   +1 more source

Evolving prokinetic therapy: New targets and therapeutic opportunities in gastrointestinal motility disorders. [PDF]

open access: yesWorld J Gastrointest Pharmacol Ther
Goyal O   +10 more
europepmc   +1 more source

Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 94-108, July 2026.
Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović   +4 more
wiley   +1 more source

Relationship Between Central Sensitization and Genetic Polymorphisms—A Case–Control Study in Fibromyalgia

open access: yesEuropean Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian   +8 more
wiley   +1 more source

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