Results 111 to 120 of about 4,051,537 (300)

Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning   +2 more
wiley   +1 more source

The Serotonin Brainstem Hypothesis for the Sudden Infant Death Syndrome.

open access: yesJournal of Neuropathology and Experimental Neurology, 2019
The sudden infant death syndrome (SIDS) is the leading cause of postneonatal infant mortality in the United States today, with an overall rate of 0.39/1000 live births. It is defined as the sudden and unexpected death of an infant
H. Kinney, R. Haynes
semanticscholar   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome

open access: yesBrain Communications, 2019
Serotonin drugs, including clemizole, have recently emerged as potential treatment options for Dravet syndrome. We synthesized a library of clemizole analogues and screened for anti-seizure activity using the zebrafish Dravet syndrome model. Coupled with
A. Griffin   +5 more
semanticscholar   +1 more source

Serotonin Syndrome with Tramadol and Dextromethorphan

open access: yes, 2007
Serotonin syndrome is an iatrogenic drug-induced synaptic serotonin concentration related toxidrome. A 29-year-old man developed agitation, tachycardia and myoclonus of limbs after an intramuscular injection of 100 mg tramadol.
MH Ng, SW Kung
core   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Methylene Blue Causing Serotonin Syndrome Following Cystocele Repair

open access: yesUrology Case Reports, 2016
Methylene blue is an intravenously administered agent that may potentiate serotonin syndrome. The usage of methylene blue to evaluate ureters for injuries and patency during urological surgeries is recognized as common practice.
Kailash Kapadia   +5 more
doaj   +1 more source

Efficacy of fenfluramine in a pediatric epilepsy patient with a pathogenic SV2A variant: A case report

open access: yesEpileptic Disorders, EarlyView.
Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori   +4 more
wiley   +1 more source

Mild serotonin syndrome: A report of 12 cases

open access: yesAnnals of Indian Academy of Neurology, 2015
Serotonin syndrome (SS) is an under diagnosed and under reported condition. Mild SS is easily overlooked by physicians. Every patient with mild SS is a potential candidate for developing life-threatening severe SS because of inadvertent overdose or the ...
S. Prakash   +4 more
semanticscholar   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

open access: yesEpilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni   +4 more
wiley   +1 more source

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