Results 181 to 190 of about 2,706,588 (275)

Serotonin Syndrome With Concomitant Antidepressant and Tramadol: A Case Report. [PDF]

Cureus
Ferreira de Lemos P, Fidalgo Maia R.
europepmc   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

A Case study of polypharmacy-induced serotonin syndrome in a cancer patient. [PDF]

J Am Assoc Nurse Pract
Zhu A, Kuhnly N, Chen L, Dulu AO.
europepmc   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

Hemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra, Jordan Fangue‐Nelon, Garima Singh   +2 more
wiley   +1 more source

Idiopathic Serotonin Syndrome - Does It Exist? [PDF]

Ann Indian Acad Neurol
Prakash S, Shah C.
europepmc   +1 more source

Brain Serotonin Content Regulates the Manifestation of Tramadol-induced Seizures in Rats: Disparity between Tramadol-induced Seizure and Serotonin Syndrome

Anesthesiology, 2015
Yohei Fujimoto, T. Funao, K. Suehiro, R. Takahashi, Takashi Mori, K. Nishikawa   +5 more
semanticscholar   +1 more source

Frequency and characteristics of multi‐domain autonomic dysfunction in patients with spontaneous intracranial hypotension

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Spontaneous intracranial hypotension (SIH) is caused by leakage of cerebrospinal fluid and often produces symptoms that worsen when standing, which may resemble autonomic disorders (conditions related to blood flow and heart rate).
Woo‐Seok Ha, Da Eun Jung, Sojung Yoon, Joonho Kim, Min Kyung Chu   +4 more
wiley   +1 more source

Serotonin Syndrome in Parkinson's Disease: Don't Get It Confused by a Tremor. [PDF]

Cureus
Martins JD, Morais Passos R, Pardal N, Carvoeiro AC, Correia F.   +4 more
europepmc   +1 more source

Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome

Brain : a journal of neurology, 2017
A. Griffin, K. Hamling, K. Knupp, SoonGweon Hong, Luke P. Lee, S. Baraban   +5 more
semanticscholar   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source