Results 11 to 20 of about 4,665 (204)

Design, Synthesis, and Biological Evaluation of Pseudo-Natural Products Inspired by Aryloctahydroindole Alkaloids. [PDF]

open access: yesChemMedChem
Mesembrine alkaloid pseudo‐natural products were synthesized employing a microwave‐assisted Diels–Alder reaction as a key step. Morphological profiling by cell painting revealed compound‐topology‐dependent mitochondrial fragmentation or inhibition of respiration.
Greiner LC   +6 more
europepmc   +2 more sources

Alterações agudas dos níveis de neurotransmissores em corpo estriado de ratos jovens após estado epiléptico induzido por pilocarpina Acute alterations of neurotransmitters levels in striatum of young rat after pilocarpine-induced status epilepticus

open access: yesArquivos de Neuro-Psiquiatria, 2003
Altas doses de agonista colinérgico muscarínico, pilocarpina, produzem alterações comportamentais, convulsões e estado epiléptico em ratos. O objetivo desse estudo foi verificar as alterações nas concentrações dos neurotransmissores em corpo estriado de ...
Rivelilson Mendes de Freitas   +4 more
doaj   +1 more source

Pathogenesis of the crosstalk between reproductive function and stress in animals—part 1: Hypothalamo–pituitary–adrenal axis, sympatho‐adrenomedullary system and kisspeptin

open access: yesReproduction in Domestic Animals, Volume 58, Issue S2, Page 176-183, September 2023., 2023
Abstract Stress is defined as a disruption of the body homeostasis in response to modest as well as perceived challenge. Two main physiological routes, the hypothalamic–pituitary–adrenal system (HPA) and the sympatho‐adrenomedullary system (SAM), aim to maintain or restore homeostasis by mutual interaction. SAM is quickly‐reacting as it primarily works
Marianne Kaiser, Laetitia Jaillardon
wiley   +1 more source

Role of Meconium in the Reaction of Airways Smooth Musculature in the Newborn with Meconium Aspiration Syndrome (Mas).

open access: yesBiomolecules & Biomedicine, 2009
The role of meconium in the respiratory system was studied in newborns, who died from various causes (250 up to 3000 g of weight). We monitored tracheal rings response to dopamine, serotonin and ethanol in different concentrations (dopamine: 0,05 mg/ml,
Hilmi Islami   +9 more
doaj   +1 more source

De la crise à une réconciliation (im)possible dans l’univers houellebecquien

open access: yesActa Universitatis Lodziensis: Folia Litteraria Romanica, 2022
L’objectif du présent article est de démontrer que malgré le pessimisme apparent de la narration, témoignant d’une société en crise, les récits de Michel Houellebecq fournissent également des indications précieuses quant à la manière dont ces crises ...
Magdalena Wojciechowska
doaj   +1 more source

Rehabilitation of the biopsychosocial concept of eustress [PDF]

open access: yesRomanian Medical Journal, 2017
Eustress concept was less used by researches at the end of XX century and really has disapeared from glossaires of books of Psychosomatics, Health Psychology and Behavioural Medicine.
Ioan-Bradu Iamandescu
doaj   +1 more source

Arresting serotonin [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
[No abstract available]
Atheir, Abbas, Bryan L, Roth
openaire   +2 more sources

Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]

open access: yes, 2002
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph   +4 more
core   +1 more source

Sérotonine de Michel Houellebecq : prédiction du destin tragique de la civilisation occidentale

open access: yesRelief: Revue Électronique de Littérature Francaise, 2019
Les romans de Michel Houellebecq sont ancrés dans les circonstances politiques et écono­miques dans lesquelles ils sont produits et consumés. L’auteur se montre un adversaire ré­solu d’une société de consommation qui fait de l’homme un robot conditionné,
Sabine van Wesemael
doaj   +5 more sources

Serotonin syndrome [PDF]

open access: yesEmergency Medicine Journal, 2007
Serotonin syndrome is an under-reported and under-recognised condition that occurs on administration of selective serotonin re-uptake inhibitors alone, or in combination with other medication known to increase levels of 5-hydroxytryptamine. This case report demonstrates signs and symptoms associated with their overdose and illustrates the importance of
Charlotte Elizabeth, Evans   +1 more
openaire   +2 more sources

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