Possible mechanisms underlying wheel-running-induced hypotensive effects
Journal of Physical Fitness and Sports Medicine, 2014 Physical activity of moderate intensity, like walking and jogging, can reduce the risk of developing metabolic syndrome and improve hypertension. However, such anti-hypertensive effects have yet to be fully studied.
Susumu Sakata +2 more
doaj +1 more source
The role of serotonin in depression—A historical roundup and future directions
Journal of Neurochemistry, Volume 168, Issue 9, Page 1751-1779, September 2024.Although depression has been studied for many decades, the exact mechanisms that lead to depression are still unknown, and available treatments only help a fraction of patients. In the 1960s, the serotonin hypothesis was published, suggesting that serotonin is the key player in depression. However, this hypothesis is being increasingly doubted. In this
Svenja Bremshey +3 more
wiley +1 more source
Treatment of depressive disorders in primary care - protocol of a multiple treatment systematic review of randomized controlled trials [PDF]
, 2011 Background: Several systematic reviews have summarized the evidence for specific treatments of primary care patients suffering from depression. However, it is not possible to answer the question how the available treatment options compare with each other
Klaus Linde +7 more
core +2 more sources
Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis
Health Science Reports, Volume 7, Issue 8, August 2024.Abstract Background and Aims Vitamin D deficiency impacts a significant proportion of the world's population, and this deficiency has been linked to various conditions characterized by imbalanced serotonin regulation. The objective of this systematic review and meta‐analysis was to evaluate the effect of vitamin D supplementation on serum serotonin ...
Malek Alimohammadi‐Kamalabadi +11 more
wiley +1 more source
Antidepressivos e suicídio nos adolescentes.
Acta Médica Portuguesa, 2011 In recent years, drug regulation agencies from the US and the UK have issued warnings concerning the emergence of suicidal behavior in children and adolescents treated with antidepressants.
Manuela Silva, Daniel Sampaio
doaj +1 more source
Transcriptional evidence for the role of chronic venlafaxine treatment in neurotrophic signaling and neuroplasticity including also Glutamatergic [corrected] - and insulin-mediated neuronal processes. [PDF]
PLoS ONE, 2014 Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the treatment of major depressive disorder (MDD).
Viola Tamási +7 more
doaj +1 more source
Obesity Reviews, Volume 25, Issue 8, August 2024.Summary Objectives To evaluate the impact of bariatric surgery on the pharmacokinetic (PK) parameters of orally administered medications and supplements. Methods Systematic searches of bibliographic databases were conducted to identify studies. Pooled effect estimates from different surgical procedures were calculated using a random‐effects model ...
Fannie Lajeunesse‐Trempe +16 more
wiley +1 more source
Citral inibe a inflamação aguda e nocicepção em camundongos: o papel dos receptores TLR4 e TLR2/DECTINA-1 [PDF]
, 2015 TCC(graduação) - Universidade Federal de Santa Catarina. Araranguá. Fisioterapia.Citral (3,7-dimethyl-2,6-octadienal), um monoterpeno de cadeia aberta e principal componente bioativo do capim limão, apresenta diferentes propriedades farmacológicas, tais ...
Gonçalves, Elaine Cristina Dalazen
core
AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol [PDF]
, 2011 OBJECTIVE: Estradiol (E2) mediates numerous beneficial effects assigned to estrogens, but whereas mechanisms have been described at the endothelial level, direct effects on vascular smooth muscle cells (VSMC) are poorly documented.
A. Rousselle +7 more
core +4 more sources
Adaptive Reaktion bei der Lösung von flexiblen Molekülen: Oligohydrate von 4‐Hydroxy‐2‐butanon
Angewandte Chemie, Volume 136, Issue 29, July 15, 2024.Die schrittweise Hydratation eines flexiblen organischen Moleküls zeigt, wie Wassersolvatisierungsgerüste, im Allgemeinen über verschiedene Strukturwege, die Substratstruktur verformen. In diesem Experiment beobachteten wir mithilfe breitbandiger Mikrowellenspektroskopie die Solvatisierung von 4‐Hydroxy‐2‐butanon mit bis zu fünf Wassermolekülen.
Meng Li +4 more
wiley +1 more source