The complexity of serotype replacement of pneumococci [PDF]
Human Vaccines & Immunotherapeutics, 2019 Pneumococci respond extremely rapidly to the vaccine pressure created by the conjugate vaccines (PCVs). Vaccine serotypes are disappearing, meanwhile new, often previously very rare types are emerging, and it is difficult to establish what makes certain serotypes more successful in replacement.
openaire +4 more sources
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo +6 more
wiley +1 more source
Progressive Changes of Vibrio Serotypes in Germ-free Mice Infected withVibrio cholerae [PDF]
, 1969 R. Bradley Sack, Carl E. Miller
openalex +1 more source
Accelerating AAV purification process development using high‐throughput resin tip module
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated viruses (AAVs) with precise genome editing and cell‐virus interaction have become a promising delivery tool for gene therapy. A robust AAV purification process is crucial for ensuring therapeutic efficacy. The challenges of AAV purification process development encompass limited material availability during early ...
Qingxuan Li +3 more
wiley +1 more source
Structural studies of mannans from Candida albicans (serotypes A and B), Candida parapsilosis, Candida stellatoidea, and Candida tropicalis [PDF]
, 1967 R. J. Yu +4 more
openalex +1 more source
Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Biotechnology Progress, EarlyView.Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao +5 more
wiley +1 more source
SEROTYPING FOR HOMOTRANSPLANTATION. VII. SELECTION OF KIDNEY DONORS FOR THIRTY‐TWO RECIPIENTS* [PDF]
, 1966 P I Terasaki +6 more
openalex +1 more source
Reactivity of Carbohydrate Phosphodiesters, Potential Targets of Antibacterial Agents
Chemistry &Biodiversity, EarlyView.A simple carbohydrate phosphodiester model was synthesized to compare the reactivity of phosphodiester bonds within carbohydrates and RNA. ABSTRACT While monosaccharide units in bacterial carbohydrates may be linked with phosphodiester bonds, human carbohydrates exclusively contain glycosidic linkages.
Eero Sillanpää +2 more
wiley +1 more source
Cell Wall Composition and Serological Reactivity of Histoplasma capsulatum Serotypes and Related Species [PDF]
, 1968 Leo Pine, Clarence J. Boone
openalex +1 more source
Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli
ChemBioChem, EarlyView.This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa +3 more
wiley +1 more source