Results 91 to 100 of about 265,799 (334)

Identification of a divergent O-acetyltransferase gene oac1b from Shigella flexneri serotype 1b strains

Emerging Microbes and Infections, 2012
Shigella flexneri is a leading cause of bacterial dysentery in developing countries. Among the 15 known serotypes, four (1b, 3a, 3b and 4b) contain a group 6 epitope due to an acetyl group connected to the O-2 position of rhamnose III on the ...
Qiangzheng Sun, Ruiting Lan, Yan Wang, Jianping Wang, Shengli Xia, Yiting Wang, Jin Zhang, Deshan Yu, Zhenjun Li, Huaiqi Jing, Jianguo Xu   +10 more
doaj   +1 more source

Additional Rhinovirus Serotypes

Experimental Biology and Medicine, 1964
SummaryFifty-two rhinovirus strains were isolated from 672 cases of acute respiratory illness in children and adults and 4 strains were recovered from well controls. Respiratory disease cases among adults which yielded a rhinovirus were nearly all upper respiratory illness (common cold) whereas the cases among children often showed lower respiratory ...
V V, HAMPARIAN, M B, LEAGUS, M R, HILLEMAN   +2 more
openaire   +2 more sources

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Serotypes With Low Invasive Potential Are Associated With an Impaired Antibody Response in Invasive Pneumococcal Disease

Frontiers in Microbiology, 2018
Pneumococcal polysaccharide vaccines may elicit a hyporesponse under certain conditions. There is limited knowledge, however, on the type of specific antibody response in individuals with invasive pneumococcal disease (IPD).
Nils Littorin, Fabian Uddén, Jonas Ahl, Jonas Ahl, Fredrik Resman, Fredrik Resman, Hans-Christian Slotved, Simon Athlin, Kristian Riesbeck   +8 more
doaj   +1 more source

Developing a serocorrelate of protection against invasive group B streptococcus disease in pregnant women: a feasibility study. [PDF]

, 2019
BACKGROUND: Group B streptococcus is the leading cause of infection in infants. Currently, intrapartum antibiotic prophylaxis is the major strategy to prevent invasive group B streptococcus disease.
Andrews, N, Carreras-Abad, C, Cochet, M, Djennad, A, Hall, T, Hamid, R, Heath, P, Khalil, A, Le Doare, K, Peregrine, E, Planche, T, Plumb, J, Ramkhelawon, L, Sheridan, E, Sivarajan, S, Vinayakarao, L, Winchester, S   +16 more
core   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Advanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang, Ruiying Qiang, Yuan Zhang, Jinxian Wan, Chen Tao, Ying Dong, Xujun Tang, Li Xu, Hairong Xiao, Yanqin Lin, Wei Tong, Ying Ma, Yongming Wang, Peng Li, Renjie Chai   +14 more
wiley   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Draft Genome Sequences of 1,183 Salmonella Strains from the 100K Pathogen Genome Project. [PDF]

, 2017
Salmonella is a common food-associated bacterium that has substantial impact on worldwide human health and the global economy. This is the public release of 1,183 Salmonella draft genome sequences as part of the 100K Pathogen Genome Project.
Arabyan, Narine, Chen, Poyin, Chin, Ning, Davis, Matthew, Foutouhi, Azarene, Foutouhi, Soraya, Huang, Bihua C, Kaufman, James, Kong, Nguyet, Ng, Whitney, Storey, Dylan B, Thao, Kao, Weimer, Bart C, Weis, Allison M, Xie, Yi   +14 more
core   +1 more source

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

Animal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li   +9 more
wiley   +1 more source

The impact of the demographic transition on dengue in Thailand: Insights from a statistical analysis and mathematical modeling [PDF]

, 2009
Background: An increase in the average age of dengue hemorrhagic fever (DHF) cases has been reported in Thailand. The cause of this increase is not known.
A Nisalak, Aidan McDermott, Ananda Nisalak, BT Grenfell, C Torrence, CP Farrington, D Schenzle, DAT Cummings, DAT Cummings, DB Fischer, Derek A. T. Cummings, DJD Earn, Donald S. Burke, DS Burke, GN Malavige, H Muench, HJ Wearing, Jeremy Farrar, JR Williams, Justin T. Lessler, K Kongsomboon, KT Thai, MG Guzman, N Ferguson, NM Ferguson, O Chareonsook, O Wichmann, P Manfredi, R Reves, Richard G. Jarman, RM Anderson, Robert V. Gibbons, Rungnapa Prasanthong, SB Halstead, SB Halstead, Sopon Iamsirithaworn, TP Endy, Y Nagao, Y Nagao   +38 more
core   +6 more sources