Results 201 to 210 of about 231,087 (360)

Salmonella brijbhumi, a new serotype from sewage

, 1963
Vinod Sharma, C. M. Singh
openalex   +1 more source

Progressive Changes of Vibrio Serotypes in Germ-free Mice Infected withVibrio cholerae [PDF]

, 1969
R. Bradley Sack, Carl E. Miller
openalex   +1 more source

Weakened Airway Epithelial Junctions and Enhanced Neutrophil Elastase Release Contribute to Age‐Dependent Bacteremia Risk Following Pneumococcal Pneumonia

Aging Cell, EarlyView.
During spread of Streptococcus pneumoniae from the lung to the bloodstream, the pneumococcal pore‐forming toxin pneumolysin (PLY) disrupts apical junction complexes (AJCs) and triggers the transmigration of polymorphonuclear leukocytes (PMNs), which secrete tissue‐destructive neutrophil elastase.
Shuying Xu, Tianmou Zhu, Hongmei Mou, Shumin Tan, John M. Leong   +4 more
wiley   +1 more source

Unexpected Serotypes of Mycoplasmas Isolated from Pigs

, 1968
D Taylor‐Robinson, Z. Dinter
openalex   +1 more source

Astrocytic Hevin/SPARCL‐1 Regulates Cognitive Decline in Pathological and Normal Brain Aging

Aging Cell, EarlyView.
Hevin/Sparcl‐1 is a synaptogenic protein secreted by astrocytes. We used adeno‐associated virus (AAV) to increase its expression in hippocampal astrocytes of APP/PSEN1 mice, an animal model for Alzheimer's disease (AD). This procedure improved cognitive performance both in the AD model and in middle‐aged wild‐type animals.
Felipe Cabral‐Miranda, Ana Paula Bergamo Araujo, Danilo Bilches Medinas, Flávia Carvalho Alcantara Gomes   +3 more
wiley   +1 more source

Clinical presentation, medical management, and outcomes in 35 hospitalized sheep diagnosed with bluetongue virus disease

Journal of Veterinary Internal Medicine
Background There is only limited information on the clinical presentation, medical management, and outcomes of hospitalized sheep diagnosed with bluetongue virus (BTV) disease.
Lisa Gamsjäger, Munashe Chigerwe
doaj   +1 more source

Bordetella pertussis Serotypes in the United States [PDF]

, 1969
Grace Eldering, Jack Holwerda, Ausma Davis, Julia M. Baker   +3 more
openalex   +1 more source

Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Aging Cell, EarlyView.
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu, Meng Ma, Lunan Luo, Feiyang Li, Jiashun Zheng, Yan Pan, Lu Yang, Ying Xiao, Ziyan Wang, Bo Xian, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

Selective Enrichment of Full AAV Capsids [PDF]

arXiv
Gene therapies using recombinant adeno-associated virus (rAAV) have been developed to treat monogenic and acquired diseases but are currently the most expensive drugs due, in part, to high manufacturing costs. The cells producing rAAV generate substantial quantities of empty (50-90%) and partially filled capsids that must be removed prior to final ...
arxiv  

SENSITIVITY TO DRUGS OF AUSTRALIAN LEPTOSPIRAL SEROTYPES [PDF]

, 1963
P. B. Spradbrow
openalex   +1 more source