Results 241 to 250 of about 54,993 (303)
Virus‐Specific Impact of Respiratory Viruses on Adult Emergency Department Outcomes
ABSTRACT Few studies have examined the impact of community‐acquired respiratory viruses (CRVs) on emergency department visits and outcomes in adults. This study aimed to characterize the epidemiology of CRV infections and assess associations between virus types and clinical outcomes.
Daijiro Nabeya +13 more
wiley +1 more source
Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit +5 more
wiley +1 more source
ABSTRACT Many currently approved gene therapies use adeno‐associated virus (AAV) to deliver DNA sequences encoding protein(s)‐of‐interest into cells. The AAV viral genome forms stable, circular DNA structures called episomes after entering the nuclei. Therapeutic proteins are then generated in vivo from transcription and translation of these episomes ...
Yuezhe Li +7 more
wiley +1 more source
This study revealed the active circulation of fowl adenoviruses in broiler farms in Sabah, Malaysia. FAdV‐8b and FAdV‐11 were identified in flocks with IBH lesions, accompanied by high antibody titres in unvaccinated birds. Phylogenetic analysis showed close relationships with global strains, highlighting the need for enhanced surveillance and control ...
Md. Safiul Alam Bhuiyan +5 more
wiley +1 more source
Evaluation of the Efficacy of Humoral Immunity Response of Killed Oil Adjuvant <i>Escherichia coli</i> Vaccine in Layer Chicken against Avian <i>E. coli</i> Serotype O<sub>78</sub> Infection. [PDF]
Saemi F +9 more
europepmc +1 more source
FMD outbreaks in dairy farms in Bishoftu were characterized by rapid within‐farm transmission (R0 = 3.7) and predominance of the SAT‐2 serotype. Current trivalent vaccination alone was insufficient for control, highlighting the need for improved vaccine matching and strengthened biosecurity measures . ABSTRACT Background Foot‐and‐mouth disease (FMD) is
Eyerusalem Fetene +7 more
wiley +1 more source
Serological surveillance revealed foot‐and‐mouth disease virus (FMDV) exposure for the first time in sheep and goats across the studied districts of Bangladesh, highlighting their critical role in FMD epidemiology. These findings emphasize the importance of including sheep and goats in national FMD surveillance and control programmes.
Tahmina Sikder +11 more
wiley +1 more source
Multidrug‐resistant Salmonella was detected in 13.5% of the raw meat samples in Chattogram, with resistance to multiple antibiotics and a high prevalence of the blaTEM gene. These findings highlight significant foodborne AMR risks and underscore the need for urgent One Health interventions to protect public health.
Mukta Das Gupta +7 more
wiley +1 more source
From Meat to Plant‐Based Products? The Enduring Impact of BSE on Beef Consumption
ABSTRACT This study reassesses the impact of the historical BSE outbreak on EU diets, showing that consumption patterns shifted persistently even after policy actions eliminated the food safety risk. Utilizing advanced difference‐in‐differences techniques on 1980–2020 data, we demonstrate that while beef consumption exhibited a transient U‐shaped ...
Jader Velásquez, Shon Ferguson
wiley +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source

