Central nervous system involvement of dengue virus is increasingly reported from endemic areas. This study describes the clinical characteristics and laboratory features of a pediatric patient enrolled in a central nervous system illness study conducted ...
Dewi Hawani Alisjahbana +10 more
doaj +1 more source
Directed evolution of adeno-associated virus 5 capsid enables specific liver tropism
Impressive achievements in clinical trials to treat hemophilia establish a milestone in the development of gene therapy. It highlights the significance of AAV-mediated gene delivery to liver.
Yuqiu Wang +14 more
doaj +1 more source
Yersinia ruckeri isolates recovered from diseased Atlantic Salmon (Salmo salar) in Scotland are more diverse than those from Rainbow Trout (Oncorhynchus mykiss) and represent distinct subpopulations [PDF]
Yersinia ruckeri is the etiological agent of enteric redmouth (ERM) disease of farmed salmonids. Enteric redmouth disease is traditionally associated with rainbow trout (Oncorhynchus mykiss, Walbaum), but its incidence in Atlantic salmon (Salmo salar) is
Burchmore, Richard +5 more
core +1 more source
Molecular Characterization of Cronobacter Lipopolysaccharide O-Antigen Gene Clusters and Development of Serotype-Specific PCR Assays [PDF]
ABSTRACT Cronobacter (formerly Enterobacter sakazakii ) is a recently defined genus consisting of six species, C. sakazakii , C. malonaticus , C. dublinensis , C.
K G, Jarvis +8 more
openaire +2 more sources
Antigenic and biochemical characterization of bovine rotavirus V1005, a new member of rotavirus serotype 10 [PDF]
Bovine rotavirus (BRV) V1005 is serologically distinct from rotavirus serotypes 1, 2, 3, 4, 5, 6, 8 and 9. BRV V1005 showed cross-reactions with BRV B223, the American prototype of serotype 10 rotavirus, and with BRV E4049, a British serotype 10 isolate.
Bruttin, Anne +5 more
core +1 more source
The rcsA gene of Klebsiella pneumoniae O1:K20 is involved in expression of the serotype-specific K (capsular) antigen [PDF]
In Klebsiella pneumoniae, the ability to synthesize large amounts of capsular polysaccharide is an important correlate of virulence. We report the cloning of rcsA from K. pneumoniae serotype O1:K20 and demonstrate that rcsA is involved in the expression of the K antigen capsule.
K L, McCallum, C, Whitfield
openaire +2 more sources
African swine fever (ASF) is an emerging disease threat to the swine industry worldwide. There is no vaccine against ASF, and progress is hindered by a lack of knowledge concerning the extent of ASFV strain diversity and the viral antigens conferring ...
Galina Koltsova +5 more
doaj +1 more source
Structure and genetics of the O-antigen ofCronobacter turicensisG3882 from a new serotype,C. turicensisO2, and identification of a serotype-specific gene [PDF]
Lipopolysaccharides on the cell surface of Gram-negative bacteria are an important factor in pathogenicity, and the O-specific polysaccharide chain (O-polysaccharide, O-antigen) defines the immunospecificity of different bacterial strains. Cronobacter turicensis is an emerging foodborne pathogen which causes severe invasive infections in neonates.
Yamin, Sun +6 more
openaire +2 more sources
Genomic diversity of pathogenic
Background Evolutionary analyses of enterohemorrhagic Escherichia coli (EHEC) have identified two distantly related clonal groups: EHEC 1, including serotype O157:H7 and its inferred ancestor O55:H7; and EHEC 2, comprised of several serogroups (O26, O111,
Qi Weihong +4 more
doaj +1 more source
Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rhoâ/â mouse
As gene therapies for various forms of retinal degeneration progress toward human clinical trial, it will be essential to have a repertoire of safe and efficient vectors for gene delivery to the target cells.
Arpad Palfi +9 more
doaj +1 more source

