Results 61 to 70 of about 118,912 (188)

Spread of Meropenem-Resistant Streptococcus pneumoniae Serotype 15A-ST63 Clone in Japan, 2012–2014

Emerging Infectious Diseases, 2018
After the introduction of pneumococcal conjugate vaccines, the incidence of pneumococcal infections due to meropenem-resistant serotype 15A-ST63 strains increased in Japan.
Satoshi Nakano, Takao Fujisawa, Yutaka Ito, Bin Chang, Yasufumi Matsumura, Masaki Yamamoto, Miki Nagao, Shigeru Suga, Makoto Ohnishi, Satoshi Ichiyama   +9 more
doaj   +1 more source

Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System [PDF]

Frontiers in Neuroanatomy, 2017
Adeno-associated viruses (AAVs) have become highly promising tools for research and clinical applications in the central nervous system (CNS). However, specific delivery of genes to the cell type of interest is essential for the success of gene therapy and therefore a correct selection of the promoter plays a very important role.
Lopez-Franco, E. (Esperanza), González-Aseguinolaza, G. (Gloria), Sucunza, D. (Diego), Vales, A. (África), Lanciego, J.L. (José Luis), Rico, A.J. (Alberto J.), Hommel, M. (Mirja), Dopeso-Reyes, I.G. (Iria G.), Vanrell, L. (Lucía), Pignataro, D. (Diego)   +9 more
openaire   +3 more sources

Genomic analysis of virulence, antimicrobial resistance, and capsular polysaccharide locus of group B Streptococcus isolated from Indonesia

The Microbe
Background: Group B Streptococcus (GBS) is one of most common pathogen infecting neonates. This study aims to analyze the genomic characteristics of GBS, including antibiotic resistance genes, virulence genes, and the capsular polysaccharide (CPS) locus,
Yustinus Maladan, Ratna Fathma Sari, Rosantia Sarassari, Sarah Azhari Balqis, Ghina Athyah Wahid, Waode Fifin Ervina, Nina Dwi Putri, Dodi Safari   +7 more
doaj   +1 more source

Characterization of Pneumococcal Genes Involved in Bloodstream Invasion in a Mouse Model. [PDF]

PLoS ONE, 2015
Streptococcus pneumoniae (the pneumococcus) continues to account for significant morbidity and mortality worldwide, causing life-threatening diseases such as pneumonia, bacteremia and meningitis, as well as less serious infections such as sinusitis ...
Layla K Mahdi, Mark B Van der Hoek, Esmaeil Ebrahimie, James C Paton, Abiodun D Ogunniyi   +4 more
doaj   +1 more source

Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae [PDF]

, 2019
The influence that bacterial adaptation (or niche partitioning) within species has on gene spillover and transmission among bacteria populations occupying different niches is not well understood.
Abbott, Abby, Almeida, Baily, Bankevich, Beerli, Beerli, Benjamini, Bertels, Bikard, Bisharat, Bishop, Bohnsack, Borchardt, Brett M Probert, Brochet, Bruen, Brynildsrud, Capella-Gutierrez, Chen, Chen, Cheng, Chiara Crestani, Chopra, Christopher D Town, Conrad, Croucher, Da Cunha, Delannoy, Delannoy, Dogan, Edgar, Enright, Erwin, Fernandez, Ferreira, Flores, Fluegge, Garrett H Springer, Gauthier, Glazko, Glazko, Greig, Guglielmini, Gupta, Hayley B Hassler, Heaps, Holt, Imperi, Inouye, Irina M Velsko, Jafar, Jaskowiak, Jeukens, Johri, Jones, Jones, Jorgensen, Joubrel, Kalimuddin, Kim, Konig, Langdon, Librado, Lin, Lindahl, Liu, Liu, Lopez-Sanchez, Loytynoja, Lyhs, Manning, Manning, Martins, Marttinen, Mather, McArthur, Md Tauqeer Alam, Michael J Stanhope, Morse, Murrell, Page, Pal, Paulina D Pavinski Bitar, Pedersen, Petrovska, Pond, Poyart, Price, Qin, Richards, Richards, Richards, Rosinski-Chupin, Ruth N Zadoks, Sahl, Sahl, Sahl, Scheffer, Schrieber, Seemann, Shannon D Manning, Shapiro, Shepheard, Sheppard, Spoor, Springman, Srivastava, Stamatakis, Stoddard, Sukhnanand, Supek, Tettelin, Tettelin, Tian, van der Mee-Marquet, Verani, Viana, Vincent P Richards, Yu, Zadoks, Zankari, Zerbino, Zhang, Zhu   +124 more
core   +2 more sources

Targeted Gene Delivery into the Mammalian Inner Ear Using Synthetic Serotypes of Adeno-Associated Virus Vectors

Molecular Therapy: Methods & Clinical Development, 2019
Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to the different cell type-specific functions.
Min-A Kim, Nari Ryu, Hye-Min Kim, Ye-Ri Kim, Byeonghyeon Lee, Tae-Jun Kwon, Jinwoong Bok, Un-Kyung Kim   +7 more
doaj   +1 more source

Antibiotic Resistance and Molecular Epidemiological Characteristics of Streptococcus agalactiae Isolated from Pregnant Women in Guangzhou, South China

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Streptococcus agalactiae colonization in pregnant women can cause postpartum intrauterine infections and life-threatening neonatal infections. To formulate strategies for the prevention and treatment of S.
Zhaomin Cheng, Pinghua Qu, Peifeng Ke, Xiaohan Yang, Qiang Zhou, Kai Lan, Min He, Nannan Cao, Sheng Qin, Xianzhang Huang   +9 more
doaj   +1 more source

Specific reprogramming of alpha cells to insulin-producing cells by short glucagon promoter-driven Pdx1 and MafA

Molecular Therapy: Methods & Clinical Development, 2023
Endogenous reprogramming of pancreas-derived non-beta cells into insulin-producing cells is a promising approach to treat type 1 diabetes (T1D). One strategy that has yet to be explored is the specific delivery of insulin-producing essential genes, Pdx1 ...
Ping Guo, Ting Zhang, Aiping Lu, Chiyo Shiota, Matthieu Huard, Kaitlyn E. Whitney, Johnny Huard   +6 more
doaj   +1 more source

Identification of the long polar fimbriae gene variants in the locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli strains isolated from humans and cattle in Argentina [PDF]

, 2010
The long polar fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. Studies have demonstrated the presence of lpf genes in several pathogenic E.
Galli, Lucía, Rivas, Marta, Torres, Alfredo G.   +2 more
core   +2 more sources

Identification and nucleotide sequence determination of the gene responsible for Ogawa serotype specificity of V. cholerae 01

FEBS Letters, 1991
The gene encoding a protein of 27 kDa, which is specifically expressed in Vibrio cholerae of serotype Ogawa, was identified and its nucleotide sequence determined. The plasmid carrying this gene was found to convert serotype specificity from Inaba to Ogawa when introduced into the Escherichia coli DH5(pVCI112) cell which harbors a cloned 20‐kilobase ...
Ito, Teruyo, Ohshita, Yoshihiro, Hiramatsu, Keiichi, Yokota, Takeshi   +3 more
openaire   +2 more sources