Results 121 to 130 of about 155,234 (391)

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

Advanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz, Jessica Cutrufello, Michael Lam, Shreya Nallaparaju, Nicholas A. Peppas   +4 more
wiley   +1 more source

Serotype distribution of Actinobacillus pleuropneumoniae isolated from porcine pleuropneumonia in the Czech Republicduring period 2003-2004

Veterinární Medicína, 2005
A total of 245 isolates of Actinobacillus pleuropneumoniae included in this study were isolated from lung tissues of pigs which died of porcine pleuropneumonia.
Z. Kucerova, Z. Jaglic, R. Ondriasova, K. Nedbalcova   +3 more
doaj   +1 more source

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, EarlyView.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

GENETIC SURVEY OF INVASIVE S. PNEUMONIAE SEROTYPES IN BULGARIA FOR A 5-YEAR PERIOD

Problems of Infectious and Parasitic Diseases, 2018
Streptococcus pneumoniae colonises the mucosal lining of the upper respiratory tract and is an important cause of invasive infections affecting young children, adults over 65 years of age, the immunocompromised and individuals with chronic diseases ...
Ivan Simeonovski, Viktoriya Levterova, Mariya Malcheva, Todor Kantardjiev   +3 more
doaj   +1 more source

Single-Reaction, Multiplex, Real-Time RT-PCR for the Detection, Quantitation, and Serotyping of Dengue Viruses

PLoS Neglected Tropical Diseases, 2013
Background Dengue fever results from infection with one or more of four different serotypes of dengue virus (DENV). Despite the widespread nature of this infection, available molecular diagnostics have significant limitations.
J. Waggoner, J. Abeynayake, M. Sahoo, L. Gresh, Y. Téllez, Karla González, Gabriela Ballesteros, A. Pierro, P. Gaibani, F. Guo, V. Sambri, Á. Balmaseda, Kumudu Karunaratne, E. Harris, B. Pinsky   +14 more
semanticscholar   +1 more source

Characterization of a Second Bovine Rotavirus Serotype [PDF]

, 1987
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Büssow, Harald, Eichhorn, Werner, Fryder, V., Marc-Martin, S., Sidoti, J.   +4 more
core   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

Diversity in the Major Polysaccharide Antigen of Acinetobacter Baumannii Assessed by DNA Sequencing, and Development of a Molecular Serotyping Scheme

PLoS ONE, 2013
We have sequenced the gene clusters for type strains of the Acinetobacter baumannii serotyping scheme developed in the 1990s, and used the sequences to better understand diversity in surface polysaccharides of the genus.
Dalong Hu, B. Liu, L. Dijkshoorn, Lei Wang, P. Reeves   +4 more
semanticscholar   +1 more source

Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307 [PDF]

, 2012
Background Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth.
A Al-Jawabreh, A Al-Jawabreh, A Al-Jawabreh, A Warburg, Abedelmajeed Nasereddin, Christophe Ravel, CL Eisenberger, CL Jaffe, DE Dobson, DF Smith, E Cupolillo, EK Saliba, EK Saliba, F Pratlong, Fouad El Baidouri, Francine Pratlong, G Anders, G Schonian, G Schonian, Gabriele Schonian, IL Mauricio, J Felsenstein, JA Rioux, JA Rioux, Jean-Pierre Dedet, JM Schwenkenbecher, K Azmi, K Azmi, Kifaya Azmi, LF Schnur, LF Schnur, LF Schnur, LF Schnur, Lionel Schnur, M Rhajaoui, M Svobodova, MZ Alam, R Maazoun, RL Jacobson, RP Soares, S Adler, S Kamhawi, S Martinez-Calvillo, SM Le Blancq, SM Le Blancq, Suheir Ereqat, Y Schlein, Y Schlein, Ziad Abdeen   +48 more
core   +2 more sources

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source