Results 91 to 100 of about 142,377 (309)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Central Serous Chorioretinopathy - an Overview.

, 2021
Central serous chorioretinopathy (CSCR) is characterised by retinal serous detachment usually localised in the macular region. CSCR predominantly affects men between 30 and 50 years of age.
Berger, L., Bühler, Virginie, Yzer, Suzanne, Berger, Lieselotte, Yzer, S., Bühler, V.   +5 more
core   +1 more source

Effectiveness of International System for Reporting Serous Fluid Cytology in Routine Practice – A Cross Sectional Study at a Tertiary Care Centre

Online Journal of Health & Allied Sciences
Background: To standardize the reporting pattern across various institutions, recently the international system for reporting serous fluid cytology (ISRSFC) was introduced.
Amita K, Ramya Suresh, Prashantha Kalappa, Sanjay M   +3 more
doaj  

Expression and clinical significance of PTK7 in ovarian serous tumors

Zhongguo aizheng zazhi, 2014
Background and purpose: The protein tyrosine kinase-7 (PTK7) gene may be related to the occurrence and progression of many tumors. This study was aimed to explore the expression of PTK7 in ovarian serous tumors and its relationship with clinical stage ...
王海燕, 印永祥, 郭庆, 韦玮, 文娟娟, 彭李博, 马恒辉, 石群立, 时姗姗, 王建东   +9 more
doaj  

Serous macular detachment in nanophthalmos: A manifestation of pachychoroid spectrum

American Journal of Ophthalmology Case Reports, 2019
Purpose: The purpose of this article is to report serous macular detachment (SMD) similar to that seen in central serous chorioretinopathy (CSCR) in patients with nanophthalmos.
Vinod Kumar, Shorya V. Azad, Rajpal Vohra, Pradeep Venkatesh   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Transpupillary thermotherapy for atypical central serous chorioretinopathy

, 2012
Ryosuke Kawamura1,2, Hidenao Ideta1, Hideyuki Hori1, Kenya Yuki2, Tsuyoshi Uno1, Tatsurou Tanabe1, Kazuo Tsubota2, Tsutomu Kawasaki11Ideta Eye Hospital, Kumamoto, Japan; 2Keio University, School of Medicine, Department of Ophthalmology, Tokyo ...
Kawasaki T, Yuki K, Hori H, Kawamura R, Tsubota K, Uno T, Tanabe T, Ideta H   +7 more
core  

Identification of a therapeutic target using molecular sequencing for treatment of recurrent uterine serous adenocarcinoma

Gynecologic Oncology Reports, 2019
Uterine serous adenocarcinoma is a rare but highly malignant form of endometrial cancer, comprising over 50% of recurrences and deaths from endometrial cancer.
Kelsey Musselman, Shannon Glynn, Juan Miguel Mosquera, Olivier Elemento, Andrea Sboner, Himisha Beltran, Kevin Holcomb   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Metastatic Serous Carcinoma of the Testis: A Case Report and Review of the Literature

Case Reports in Oncology, 2011
Serous tumours of the testis and paratestis are rare, with fewer than 50 cases reported in the literature. The majority of the reported cases have been borderline serous tumours, and these tend not to recur or metastasize.
Yuk Ting Ma, Shalini Chaudhri, Michael H. Cullen   +2 more
doaj   +1 more source