Results 101 to 110 of about 142,377 (309)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Central serous papillopathy by optic nerve head drusen

, 2010
Ana Marina Suelves1, Ester Francés-Muñoz1, Roberto Gallego-Pinazo1, Diamar Pardo-Lopez1, Jose Luis Mullor2, Jose Fernando Arevalo3, Manuel Díaz-Llopis1,4,51Department of Ophthalmology, La Fe University Hospital, Valencia,
Ester Francés-Muñoz, et al, Ana Marina Suelves, Roberto Gallego-Pinazo   +3 more
core  

Investigação do fenótipo das células presentes nos líquidos cavitários para o diagnóstico diferencial entre as efusões malignas e as benignas [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.As membranas serosas pleurais, peritoneais e pericárdicas são aquelas que envolvem, respectivamente ...
Reis, Manoela Lira
core  

Methods to preserve fertility in patients with serous borderline ovarian tumors

Клинический разбор в общей медицине
Over the past decades, there have been great advances in the understanding of serous borderline tumors of the ovary. Although most serous borderline tumors have a favorable outcome, recurrence and progression to carcinoma are possible.
Mekan R. Orazov , Marina V. Kiseleva , Vladlena M. Pernay   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A study of the predictive value of morphometric assessments in clinical outcome in ovarian epithelial malignancy [PDF]

Quantitative pathology as a tool in gynaecological pathology is fairly new. Such techniques allow greater objectivity than histological grading, typing, and residual tumour estimation.
Palmer, Julia Elizabeth
core  

Research Developments on the Histopathology and Prognostic Predictors of Serous Borderline Tumor of Ovary

Cancer Biology & Medicine, 2009
Serous borderline tumor of ovary (SBT) includes two subtypes of typical serous borderline tumor and micropapillary variant, which have different histopathology features.
Xinlan SHI, Chunxiang ZHAO
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Assessing the Diagnostic Value of VEGF Levels in Differentiation of Malignant Serous Discharge (Positive Cytology) from Benign Serous Discharge (Negative Cytology) Using ELISA Method

مجله دانشکده پزشکی اصفهان, 2012
Background: One of the factors effective on tumor cell growth and proliferation is vascular endothelial cell growth factor (VEGF). It also affects the formation of serous fluids such as ascites or pleural effusion through vascular permeability.
Noushin Afshar Moghaddam, Reza Soloukiا, Pouya Akbari   +2 more
doaj  

Expression and clinical value of EIF3CL in serous ovarian cancer

Journal of International Medical Research
Objectives This study aimed to explore the expression of eukaryotic translation initiation factor 3 subunit C-like in serous ovarian cancer samples (both paraffin-embedded and fresh samples) and evaluate its clinical value in patients with serous ovarian
Tingting Li, Longyang Liu, Qudi Qiao, Zhongqiu Lin, Jianhuan Yuan, Zhaoyang Zeng, Jilong Yao   +6 more
doaj   +1 more source