Results 131 to 140 of about 10,966 (204)

Case report of a novel alpha1-antitrypsin null variant in Türkiye: Q0RİZE

BMC Pulmonary Medicine
Background Alpha1-antitrypsin (AAT) is a serine protease inhibitor that serves as a counterbalance to the activity of elastases, e.g., neutrophil elastase in lung tissue.
Dilek Karadoğan, Ünal Şahin, Bettina Dreger, Laura Grandoso, Lourdes Osaba   +4 more
doaj   +1 more source

Serpina1e mediates the exercise-induced enhancement of hippocampal memory

Abstract The exercise-induced enhancement of learning and memory is thought to be regulated by body‒brain interactions via secretory proteins in the blood plasma1,2. Given the prominent role that skeletal muscle plays during exercise, the beneficial effects of exercise on cognitive functions appear to be mediated by muscle-derived secretory ...
Hyungju Park, Hyunyoung Kim, Sanghee Shin, Jeongho Han, Jong-Seo Kim   +4 more
openaire   +1 more source

超声血流成像结合血清SERPINA1、IFITM1在鉴别子宫肌瘤与子宫腺肌症中的应用价值

Zhongguo shiyan zhenduanxue
目的探究超声血流成像结合血清丝氨酸蛋白酶抑制剂A1（SERPINA1）、干扰素诱导跨膜蛋白1（IFITM1）在鉴别子宫肌瘤与子宫腺肌症中的应用价值。方法选取2021年12月至2022年12月在齐齐哈尔市中医医院经病理确诊的子宫肌瘤患者120例与子宫腺肌症患者90例以及同期健康体检女性60例。所有研究对象均接受经阴道彩色多普勒超声检查。记录子宫及病灶（子宫肌瘤组、子宫腺肌症组）内部及周边，子宫相应区域的收缩期峰值血流速度（PSV）、阻力指数（RI）及搏动指数（PI ...
刘柏, 周苗苗, 李古月, 张红秋
doaj  

Resistance Heterogeneity and Small Airway Asthma Phenotype [PDF]

, 2019
Kuo, Chris, Lipworth, Brian
core   +3 more sources

SERPINA1 drives TACE resistance in hepatocellular carcinoma by competitively binding ITGB3 to block ITCH-mediated ubiquitination and degradation. [PDF]

Cell Oncol (Dordr)
Zhang L, Bai X, Du M, Dou W, Xie Z, Liu J, Hou Y.   +6 more
europepmc   +1 more source

Clinical implications of a novel SERPINA1 variant c.236 T > A: Challenges in characterizing new rare alpha-1 antitrypsin mutations. [PDF]

Mol Genet Metab Rep
Olivares-Rivera A, Ersöz H, Höger P, Veith M, Greulich T, Schlamp K, Janciauskiene S, Herth F, Trudzinski FC.   +8 more
europepmc   +1 more source

RNA editing for the treatment of alpha-1 antitrypsin deficiency. [PDF]

Nucleic Acids Res
Monian P, Shivalila C, Lu G, Bowman K, Briem S, Bylsma M, Byrne M, Cannon M, Chatterjee A, Dallaire M, Desai J, Dufresne J, Faraone A, Favaloro F, Friend S, Ghosh A, Godfrey J, Hernandez N, Huth O, Iwamoto N, Kawamoto T, Lamattina A, Lemaitre M, Lindsey A, Liu F, Looby R, Luu K, McGlynn A, Metterville J, Paik IH, Pan Q, Patil S, Pu T, Purcell-Estabrook E, Ranade A, Rheinhardt J, Rossi J, Shimizu M, Singh K, Standley S, Thomas C, Tripathi S, Yang H, Yordanoff R, Yin Y, Yu H, Narayanan P, Kandasamy P, Giangrande PH, Vargeese C.   +49 more
europepmc   +1 more source

Machine learning-derived identification of an obesity and lipid metabolism-related genes signature for the diagnosis and molecular typing of acute myocardial infarction. [PDF]

Front Cardiovasc Med
Li J, Xue Z, Zhang M, Lu F, Ji S.
europepmc   +1 more source

Complement activation and fibrinolysis dysregulation drive contrast-induced acute kidney injury: a 4D proteomics rat study. [PDF]

Ren Fail
Yang Q, Sun L, Zhang Z, Yan Z, Zhang J, Hu J, Ding X.   +6 more
europepmc   +1 more source

Complement and Coagulation Cascades Pathway was Inactivated in HIV-Associated Colorectal Cancer: Results from a Proteomics Study. [PDF]

J Cancer
Lian S, Li L, Yang Y, Liu S, Song S, Zhang L.   +5 more
europepmc   +1 more source