Results 121 to 130 of about 10,966 (204)

Identification of Novel Short C-Terminal Transcripts of Human SERPINA1 Gene

PLOS ONE, 2017
Human SERPINA1 gene is located on chromosome 14q31-32.3 and is organized into three (IA, IB, and IC) non-coding and four (II, III, IV, V) coding exons. This gene produces α1-antitrypsin (A1AT), a prototypical member of the serpin superfamily of proteins.
Nerea Matamala, Nupur Aggarwal, Paolo Iadarola, Marco Fumagalli, Gema Gomez-Mariano, Beatriz Lara, Maria Teresa Martinez, Isabel Cuesta, Jan Stolk, Sabina Janciauskiene, Beatriz Martinez-Delgado   +10 more
openaire   +8 more sources

Accurate Indentification of Pathogenic Mutations Conferring α1-Antitrypsin Deficiency by a Novel Multiplexed Molecular AssayTake-home Points

CHEST Pulmonary
Background: α1-Antitrypsin deficiency (AATD) is a common, underdiagnosed disease caused by mutations in the polymorphic SERPINA1 gene. AATD often causes COPD, other respiratory ailments, and severe liver disease.
Emily K. DeCurtis, BSc, Sharon K. Kuss-Duerkop, PhD, Iara M.P. Machado, PhD, Zoe P. Stewart, BSc, Matt Jackson, MS, Ellie Hasenohr, BSc, Jessica L. Crumby, BSc, Steve D. Groshong, MD, PhD, Claire M. Coeshott, PhD, Ronald J. Harbeck, PhD, James P. Woodrow, MD, Robert A. Sandhaus, MD, PhD, Yongbao Wang, PhD   +12 more
doaj   +1 more source

Evaluation of Congo red staining kit to determine proteinuria in preeclampsia [PDF]

, 2018
Plantear la posible utilidad del uso de la tinción de Rojo Congo en el diagnóstico de proteinuria en casos de preeclampsia.Introduction: Preeclampsia is characterised by the increased excretion of misfolding protein, attracted by a Diazo dye denominated ...
Angeles Vázquez, María de Jesús, Angeles Vázquez, María de Jesús, Fuentes Gutiérrez, Erika Karina, Fuentes Gutiérrez, Erika Karina, Mendieta Zerón, Hugo, Mendieta Zerón, Hugo, RODRIGUEZ CHAVEZ, JOSE LUIS, RODRIGUEZ CHAVEZ, JOSE LUIS   +7 more
core  

Serum α1-AT Levels and SERPINA1 Molecular Analysis in Breast Cancer: An Experimental and Computational Study

Diseases
Background/Objectives: Breast cancer (BC) is a heterogeneous disease with multifactorial origins, including environmental, genetic, and immunological factors.
Guadalupe Ávalos-Navarro, Luis A. Bautista-Herrera, Asbiel Felipe Garibaldi-Ríos, Ramiro Ramírez-Patiño, Marisol Gutiérrez-García, Perla Briseño-Álvarez, Luis Felipe Jave-Suárez, Emmanuel Reyes-Uribe, Martha Patricia Gallegos-Arreola   +8 more
doaj   +1 more source

Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis [PDF]

, 2011
Our laboratory’s previous microarray analysis of subjects with Plasmodium falciparum revealed up-regulation of Toll-like receptor, NF-kB, TNF-α, IFN-γ, IL-1β, p38 MAPK, and MHC molecules.
Alan Scott, Anne Jedlicka, August Louis Bourgeois, Nathan Wolfe, Sher Singh, Wan-Chung(Wan-Jiung) Hu   +5 more
core   +1 more source

SERPINA1 Gene [PDF]

, 2020
openaire   +1 more source

Interactions between single nucleotide polymorphism of SERPINA1 gene and smoking in association with COPD: a case–control study

International Journal of COPD, 2017
Xiaowei Deng,1 Cun-hua Yuan,1 De Chang2 1Health Medical Center, 2Department of Respiratory Medicine, General Hospital of Chinese People’s Armed Police Forces, Beijing, People’s Republic of China Background: SERPINA1 gene has been implicated
Deng XW, Yuan CH, Chang D
doaj  

Serpin peptidase inhibitor, clade A (SERPINA1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

α1-Antitrypsin (SERPINA1; AAT; A1AT) [PDF]

Science-Business eXchange, 2010
openaire   +2 more sources

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. [PDF]

, 2019
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery efforts6-11.
23andMe Research Team, Bjornsdottir, Gyda, Boardman, Jason D, Boehnke, Michael, Boomsma, Dorret I, Brazel, David M, Chen, Chu, Chen, Fang, Choquet, Hélène, Cucca, Francesco, Datta, Gargi, Davies, Gareth E, Davila-Velderrain, Jose, Docherty, Anna R, Eaton, Charles B, Ehringer, Marissa A, Esko, Tõnu, Faul, Jessica D, Fiorillo, Edoardo, Foerster, Johanna R, Fritsche, Lars G, Gabrielsen, Maiken Elvestad, Gillespie, Nathan A, Gordon, Scott D, Gudbjartsson, Daniel F, Haessler, Jeffrey, Haller, Toomas, Harris, Kathleen Mullan, Heath, Andrew C, Hewitt, John K, Hickie, Ian B, Hokanson, John E, Hopfer, Christian J, Hottenga, Jouke-Jan, Huang, Hongyan, HUNT All-In Psychiatry, Hunter, David J, Iacono, William G, Jang, Seon-Kyeong, Jansen, Philip R, Jiang, Yu, Johnson, Eric O, Kamatani, Yoichiro, Kardia, Sharon LR, Keller, Matthew C, Kellis, Manolis, Kooperberg, Charles, Kraft, Peter, Krauter, Kenneth S, Laakso, Markku, Li, Yue, Lind, Penelope A, Ling, Yueh, Liu, Mengzhen, Loukola, Anu, Lutz, Sharon M, Madden, Pamela AF, Martin, Nicholas G, Matoba, Nana, McGue, Matt, McGuire, Daniel, McMahon, George, McQueen, Matthew B, Medland, Sarah E, Metspalu, Andres, Mohlke, Karen L, Mulas, Antonella, Mägi, Reedik, Nielsen, Jonas B, Okada, Yukinori, Orrù, Valeria, Palviainen, Teemu, Pandit, Anita, Peters, Ulrike, Polderman, Tinca JC, Posthuma, Danielle, Reginsson, Gunnar W, Reiner, Alexander P, Rice, John P, Rimm, Eric, Rose, Richard J, Runarsdottir, Valgerdur, Skogholt, Anne Heidi, Smith, Jennifer A, Stallings, Michael C, Stančáková, Alena, Stefansson, Hreinn, Taylor, Amy E, Thai, Khanh K, Tian, Chao, Tindle, Hilary A, Turman, Constance, Wedow, Robbee, Willemsen, Gonneke, Young, Hannah, Young, Kendra A, Zajac, Gregory JM, Zhan, Xiaowei, Zhao, Wei, Zhou, Wei   +99 more
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