Results 101 to 110 of about 10,966 (204)
Development and characterization of a new human hepatic cell line [PDF]
, 2015 The increasing demand and hampered use of primary human hepatocytes for research purposes have urged scientists to search for alternative cell sources, such as immortalized hepatic cell lines.
Berx, Geert +6 more
core +3 more sources
Brain and Behavior, Volume 16, Issue 4, April 2026.This study used two‐sample Mendelian randomization to assess causal relationship of immune cells with NMOSD. We then enrolled 27 NMOSD patients and 17 healthy controls for peripheral blood flow cytometric analyses to validate part of MR findings. ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) are an immune‐mediated inflammatory ...
Jingru Ren +8 more
wiley +1 more source
Potential of human induced pluripotent stem cells in studies of liver disease. [PDF]
, 2015 Liver disease is a leading cause of death in the Western world. However, our insight into the underlying disease mechanisms and the development of novel therapeutic agents has been hindered by limited availability of primary tissue, intraspecies ...
Sampaziotis, Fotios +2 more
core +2 more sources
Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.ABSTRACT Cell recognition and uptake of extracellular vesicles (EVs) is mediated by a variety of surface molecules. Growing interest has recently been drawn towards glycan structures on EVs. Hyaluronic acid (HA) is a negatively charged glycosaminoglycan that can decorate the surface of EVs from different origins.
Heikki Kyykallio +10 more
wiley +1 more source
Network analysis of quantitative proteomics on asthmatic bronchi: effects of inhaled glucocorticoid treatment [PDF]
, 2011 Background Proteomic studies of respiratory disorders have the potential to identify protein biomarkers for diagnosis and disease monitoring. Utilisation of sensitive quantitative proteomic methods creates opportunities to determine individual patient ...
Serena E O'Neil +9 more
core +1 more source
Journal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 4, Page 284-293, April 2026.Masuda and colleagues showed that perihilar cholangiocarcinoma near the hilar plate is biologically heterogeneous. Tumors without a gross intrahepatic mass resembled extrahepatic cholangiocarcinoma, whereas those with a gross intrahepatic mass demonstrated an intrahepatic molecular profile, indicating distinct biological subgroups and providing insight
Yuki Masuda +9 more
wiley +1 more source
Screening for Alpha 1 antitrypsin deficiency in Tunisian subjects with obstructive lung disease: a feasibility report [PDF]
, 2009 Background AATD is one of the most common inherited disorders in the World. However, it is generally accepted that AATD in North African populations is not a risk factor for lung and/or liver disease, based on a number of small studies.
Chibani Jemni +11 more
core +1 more source
MedComm, Volume 7, Issue 4, April 2026.This study presents the first spatially resolved proteomic map of diabetic vasculopathy, identifying distinct molecular signatures in aortic regions. The glucocorticoid receptor/dipeptidase 1 (GR/DPEP1) axis was identified as a novel driver of diabetic vascular inflammation and dysfunction.
Chak Kwong Cheng +9 more
wiley +1 more source
PLoS ONE, 2023 Alpha-1 antitrypsin deficiency (AATD), a relatively common autosomal recessive genetic disorder, is underdiagnosed in symptomatic individuals. We sought to compare the risk of liver transplantation associated with hepatitis C infection with AATD ...
Bryce A. Schuler +5 more
doaj
Non-specific physiological background effects of acupuncture revealed by proteomic analysis in normal rats [PDF]
, 2014 BACKGROUND: The total effects of adequate real acupuncture treatment consist of pathologic-specific and non-specific physiological effects. The latter may be the fundamental component of the therapeutic effects of acupuncture. This study investigated the
Gyoung-Hee Park +6 more
core +1 more source