Results 121 to 130 of about 27,731 (238)

Maturation-associated changes in Sertoli cells following <i>in vitro</i> culture of frozen-thawed prepubertal mouse testicular tissue. [PDF]

Front Reprod Health
Moutard L, Dufour M, Rives N, Basille-Dugay M, Chemin E, Rousseau V, Feraille A, Rondanino C, Dumont L.   +8 more
europepmc   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Comparison of Sertoli cells in duck testes pre- and post-sexual maturation. [PDF]

Poult Sci
Tao Z, Xu W, Song W, Lu L, Zhang S, Liu H, Wang Z, Gu H, Zhu C, Li H.   +9 more
europepmc   +1 more source

The Local Effects of Systemic Therapies in Urological Oncology: A Systematic Review

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Systemic therapies can impact local disease progression in genitourinary malignancies, potentially reducing the necessity for extensive surgery. Understanding these effects is crucial for optimizing treatment approaches in urologic oncology.
Sharon Nordheimer, Ofer N. Gofrit
wiley   +1 more source

Depicting the dynamic transcriptional and epigenetic landscape of testis development in pubertal Simmental cattle. [PDF]

J Anim Sci Biotechnol
Zhang J, Qi X, Zhao W, Yuan S, Hai N, Yu L, Hua J, Yu D, Wei Y.   +8 more
europepmc   +1 more source

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 501-509, August 2026.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell, Antonio Lombardi, William Brumskine, Lali Mikiashvili, Kim Boekelheide, Joanna Moreira, Alda Holsta, Matthew Betteridge, Lindsay Thompson, Angela Crook, Paul Bruinenberg, Maria Beumont, Eugene Sun, Francesca Conradie   +13 more
wiley   +1 more source

Single-Cell RNA Sequencing Reveals Dynamic Transcriptional Landscape of Testicular Maturation in Dezhou Donkeys. [PDF]

Animals (Basel)
Wang Z, Yu J, Liu G, Jafari H, Li C, Yang G, Lei C, Dang R.   +7 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

N-salicyloyl tryptamine derivative ameliorates spermatogenic dysfunction in obese mice by attenuating insulin resistance, enhancing Sertoli cell glycolysis, and inhibiting apoptosis: an <i>in vivo</i> and <i>in vitro</i> study. [PDF]

Front Cell Dev Biol
Fu Z, Pan Y, Huang Q, Wu H, Cai Y, Yang C, Lei X, Wang Z, Yang F, Hu L.   +9 more
europepmc   +1 more source

Serine Ameliorates Cadmium‐Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Serine mitigates cadmium‐induced testicular injury in mice by inhibiting the PGAM1/PHGDH pathway, restoring ion homeostasis and glycolysis, and relieving oxidative stress, inflammation, fibrosis, and apoptosis. ABSTRACT Cadmium (Cd) is a widespread environmental contaminant that impairs male reproductive function; however, the metabolic mechanisms ...
Xueru Wang, Na Luo, Yonggang Ma, Hui Zou, Xishuai Tong, Jiaqiao Zhu, Ruilong Song, Hongyan Zhao, Zongping Liu   +8 more
wiley   +1 more source