Results 31 to 40 of about 38,291 (273)
Sertoli-specific Lrh1 conditional mutant testes develop tubulogenesis defects perinatally.
, 2022 (A-F) IF staining of testis sections for Sertoli marker SOX9 (green) and DAPI (blue) comparing controls lacking Cre and Dhh-Cre deleted Lrh1 mutants. (A,B) E15.5, (C,D) E18.5, (E,F).
Vivian J. Bardwell (12119794) +7 more
core +1 more source
The Testicular-Derived Sertoli Cell: Cellular Immunoscience to Enable Transplantation
Cell Transplantation, 2003 There is a renewed enthusiasm for the potential of cellular transplantation as a therapy for numerous clinical disorders. The revived interest is largely due to the unprecedented success of the “Edmonton protocol,” which produced a 100% cure rate for ...
Dwaine F. Emerich PH.D +2 more
doaj +1 more source
Scientific Reports, 2022 AbstractThe Sertoli cell (SC)-specific knockout (KO) of connexin43 (Cx43) was shown to be an effector of multiple histological changes in tubular morphology, resulting in germ cell loss through to a Sertoli-cell-only (SCO) phenotype and vacuolated seminiferous tubules containing SC-clusters.
Sarah Staggenborg +11 more
openaire +3 more sources
TUMOR TESTICULAR CALCIFICANTE DE CELULAS GRANDES DE SERTOLI: COMUNICACION DE UN CASO
Revista Chilena de RadiologíaSe presenta el caso de un paciente de 7 años con tumor testicular calcificante, de células grandes de Sertoli, multifocal y bilateral, diagnos-ticado con ultrasonografía, en el contexto de una historia familiar de Complejo de Carney, tratado con ...
Alonso Inzulza C, Yerka Krstulovic
doaj +1 more source
A Human Gonadal Cell Model From Induced Pluripotent Stem Cells
Frontiers in Genetics, 2018 Sertoli cells are main players in the male gonads development and their study may shed light on 46,XY disorders of sex development (DSD). Mature primary Sertoli cells are incapable of proliferating in prolonged in vitro cultures and the available Sertoli
Daniel Rodríguez Gutiérrez +3 more
doaj +1 more source
Activin A and Sertoli Cells: Key to Fetal Testis Steroidogenesis
, 2022 The long-standing knowledge that Sertoli cells determine fetal testosterone production levels is not widespread, despite being first reported over a decade ago in studies of mice.
Loveland, Kate L +5 more
core +1 more source
Asian Journal of Andrology, 2015 This study was designed to explore the regulatory effects of male germ cell secreting factor NODAL on Sertoli cell fate decisions from obstructive azoospermia (OA) and nonobstructive azoospermia (NOA) patients.
Ru-Hui Tian +12 more
doaj +1 more source
Sertoli cell tumor in patient with multiple intratesticular cysts
Urology Case Reports, 2022 Sertoli cell tumor is a rare type of testicular tumor. In this study, a 70-year-old man was presented with a Sertoli cell tumor with non-classical findings. The patient noticed progressive swelling on the left hemiscrotum.
Farzad Allameh +3 more
doaj +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Stem Cell Research & Therapy, 2019 Background Sertoli cells are the most important somatic cells contributing to the microenvironment (named niche) for spermatogonial stem cells (SSCs). They produce amounts of crucial growth factors and structure proteins that play essential roles in the ...
Ruhui Tian +11 more
doaj +1 more source