Results 21 to 30 of about 32,541 (263)

Absence of inhibin alpha and retinoblastoma protein leads to early sertoli cell dysfunction. [PDF]

open access: yesPLoS ONE, 2010
Sertoli cells, the support cells of mammalian spermatogenesis, are regulated by a number of nuclear factors and express retinoblastoma (RB) tumor suppressor protein.
Roopa L Nalam   +2 more
doaj   +1 more source

The Molecular Mechanism of Sex Hormones on Sertoli Cell Development and Proliferation

open access: yesFrontiers in Endocrinology, 2021
Sustaining and maintaining the intricate process of spermatogenesis is liable upon hormones and growth factors acting through endocrine and paracrine pathways.
Wasim Shah   +7 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen. [PDF]

open access: yesPLoS ONE, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Peter J O'Shaughnessy   +2 more
doaj   +1 more source

Sertoli cell tumor in patient with multiple intratesticular cysts

open access: yesUrology Case Reports, 2022
Sertoli cell tumor is a rare type of testicular tumor. In this study, a 70-year-old man was presented with a Sertoli cell tumor with non-classical findings. The patient noticed progressive swelling on the left hemiscrotum.
Farzad Allameh   +3 more
doaj   +1 more source

Icariin Improves Age-Related Testicular Dysfunction by Alleviating Sertoli Cell Injury via Upregulation of the ERα/Nrf2-Signaling Pathway

open access: yesFrontiers in Pharmacology, 2020
Sertoli cells play crucial roles in spermatogenesis and are impaired by aging. Icariin, a flavonoid from Epimedium, has been reported to exhibit anti-aging effects and improve testicular dysfunction in the clinical setting.
Haixia Zhao   +14 more
doaj   +1 more source

Dysregulation of Immature Sertoli Cell Functions by Exposure to Acetaminophen and Genistein in Rodent Cell Models

open access: yesCells, 2023
Sertoli cells are essential for germ cell development and function. Their disruption by endocrine disrupting chemicals (EDCs) or drugs could jeopardize spermatogenesis, contributing to male infertility. Perinatal exposure to EDCs and acetaminophen (APAP)
Maia Corpuz-Hilsabeck   +2 more
doaj   +1 more source

Sertoli Cell-Specific Activation of Transforming Growth Factor Beta Receptor 1 Leads to Testicular Granulosa Cell Tumor Formation

open access: yesCells, 2023
The transforming growth factor β (TGFβ) superfamily, consisting of protein ligands, receptors, and intracellular SMAD transducers, regulates fundamental biological processes and cancer development.
Xin Fang   +5 more
doaj   +1 more source

Androblastoma—Sertoli Cell Tumor

open access: yesJournal of Urology, 1974
An androblastoma in an undescended testicle of a 43 yr old man is reported. Microscopically, the tumor showed zones of neoplastic cells varying in size and shape and separated by fibrous tissue. In some areas the cells were round with eosinophilic cytoplasm and round nuclei. No mitoses were seen.
Kalis, E.G., Goulandris, N.D.
openaire   +3 more sources

RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells

open access: yesCell & Bioscience, 2023
Background Spermatogenesis depends on the supporting of the Sertoli cells and their communications with germ cells. However, the regulation of crosstalk between the Sertoli cells and germ cells remains unclear. Results In this report, we used conditional
Fengling Lai   +10 more
doaj   +1 more source

THE EFFECT OF PREDNISONE ON SERTOLI CELL OF CONTRALATERAL TESTICULAR TORSION

open access: yesJurnal Urologi Indonesia, 2012
Objective: To evaluate the effect of prednisone in unilateral testicular torsion on Sertoli cell quality of contralateral testis. Material & Method: Thirty Wistar rats were divided into three groups i.e.
Dandy Tanuwidjaja   +4 more
doaj   +1 more source

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