Results 91 to 100 of about 59,858 (305)
Scientific ReportsCortisol/corticosterone (CORT) are typical glucocorticoids and exert an anti-stress function. p27, a cyclin-dependent kinase inhibitor, acts as a terminal factor for Sertoli cell proliferation at the prepubescent stage. Our previous study showed neonatal
Hidenobu Miyaso +10 more
doaj +1 more source
AMHR2 mutation in persistent Müllerian duct syndrome: A case of transverse testicular ectopia
UroPrecision, EarlyView.Abstract Backgroud Persistent Müllerian duct syndrome (PMDS) is a rare condition characterized by the persistence of Müllerian duct structures in genotypic and phenotypic males. Case Presentation We present the case of a 4‐month‐old male with PMDS who presented with transverse testicular ectopia. The patient underwent diagnostic laparoscopic orchiopexy
Hangcheng Fu +2 more
wiley +1 more source
Identification of a Specific Sertoli Cell Marker, Sox9, for Use in Transplantation
Cell Transplantation, 2002 The immunoprivileged environment of the testes was first described in the 1930s, and the Sertoli cell was later identified as the main cell type responsible for this phenomenon. Recent work has examined the possibility of recreating this immunoprivileged
R. A. Hemendinger +4 more
doaj +1 more source
Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]
, 2015 Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee +6 more
core +2 more sources
Andrology, EarlyView.Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas +6 more
wiley +1 more source
Zika virus infection in semen: Effect on human reproduction [PDF]
, 2017 Unique among vector-borne flaviviruses, Zika virus can infect testis and male genital tract, can persist in semen for months after symptoms onset, and be sexually transmitted.
Barzon, Luisa +2 more
core +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, EarlyView.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Sertoli Cells Induce Systemic Donor-Specific Tolerance in Xenogenic Transplantation Model
Cell Transplantation, 2006 Cell therapy is a potentially powerful tool in the treatment of many grave disorders including leukemia, immune deficiencies, autoimmune diseases, and diabetes.
R. Shamekh +5 more
doaj +1 more source
Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source