Abstract Objectives Hereditary polyposis syndromes in children are rare, heterogeneous disorders associated with significant morbidity and long‐term risk of malignancy. Current data on their presentation, management, and outcomes in pediatric populations remain limited.
Shlomi Cohen +9 more
wiley +1 more source
Efeito do 3,5,3' -triiodo-l-tironina nas proteínas dos filamentos intermediários de testículos de ratos durante o desenvolvimento sexual [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.As células de Sertoli têm um importante papel no desenvolvimento e na manutenção da espermatogênese em testículos de ...
Zamoner, Ariane
core
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Sertoli Cells Induce Systemic Donor-Specific Tolerance in Xenogenic Transplantation Model
Cell therapy is a potentially powerful tool in the treatment of many grave disorders including leukemia, immune deficiencies, autoimmune diseases, and diabetes.
R. Shamekh +5 more
doaj +1 more source
Effect of FSH and insulin on lipogenesis in cultures of Sertoli cells from immature rats
Follicle-stimulating hormone (FSH) and insulin regulate glycide metabolism in Sertoli cells, thus stimulating lactate production. These stimulatory effects of FSH and insulin do not require protein synthesis, suggesting a modulation of enzyme activity ...
F.C.R. Guma +3 more
doaj +1 more source
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida +7 more
wiley +1 more source
Collagen biosynthesis in cultured rat testicular Sertoli and peritubular myoid cells
The incorporation of 3H-proline into protein was regarded as a measure of total protein synthesis and the incorporation into hydroxyproline as indicative of collagen synthesis.
Irving, Michael G. +4 more
core +1 more source
Abstract Background Viral infections have been identified as potential disruptors of male reproductive health. This study aimed to investigate the prevalence of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV‐6), and herpes simplex virus types 1 and 2 (HSV‐1/2) DNA in semen samples from fertile and infertile men within the potential impact of ...
Seyedeh Zahra Hashemi +7 more
wiley +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel +5 more
core +1 more source

