Results 111 to 120 of about 52,947 (295)

Sertraline-Induced Optic Nerve Dysfunction [PDF]

open access: diamond, 2023
Ismail Abuallut   +2 more
openalex   +1 more source

Predicting Response to Pro‐Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are often associated with persistent cognitive deficits that impair psychosocial functioning. While pro‐cognitive interventions show promise, trial findings are inconsistent, potentially due to baseline factors influencing treatment response.
Dimosthenis Tsapekos   +30 more
wiley   +1 more source

Ecchymosis due to sertraline use: a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Sertraline is a widely used antidepressant due to its low adverse effect profile. Hematological adverse effects related to sertraline are uncommon. This report includes a case which presented to an emergency department with a large ecchymotic lesion on ...
Orhan Cinar   +4 more
doaj  

What is the therapeutic value of antidepressants in dementia? A narrative review [PDF]

open access: yes, 2016
Objectives: Antidepressants are commonly used in dementia. Depression is a frequent and important co-morbidity in dementia and antidepressants are often used to treat depression and more widely.
Auchus   +88 more
core   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome. [PDF]

open access: yes, 2020
BackgroundThe purpose of this study was to conduct a 20-week controlled trial of lovastatin (10 to 40 mg/day) in youth with fragile X syndrome (FXS) ages 10 to 17 years, combined with an open-label treatment of a parent-implemented language intervention (
Abbeduto, Leonard   +10 more
core  

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang   +2 more
wiley   +1 more source

The preventive role of wheat germ oil against sertraline‐induced testicular damage in male albino rats

open access: yesAndrologia, 2019
Sertraline is an antidepressant medication used extensively in the therapy of depression. The present investigation was intended to estimate the actual protective role of wheat germ oil on sertraline‐caused testicular injury in albino rats.
H. Hamdi
semanticscholar   +1 more source

The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases

open access: yesJournal of Lipid Research
Phosphatidic acid phosphatase (PAP) is an evolutionarily conserved eukaryotic enzyme that catalyzes the Mg2+-dependent dephosphorylation of phosphatidic acid to produce diacylglycerol.
Geordan J. Stukey   +9 more
doaj   +1 more source

Emerging pharmacotherapy of tinnitus [PDF]

open access: yes, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen   +43 more
core   +1 more source

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