Results 131 to 140 of about 31,475 (230)

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva, Vitória Barros Marques, Fernanda Karoline Oliveira da Silva, Maele Oliveira de Sena, Yanka do Vale Carvalho, Bruna da Silva Figueiredo, Luana Talinne da Costa Gomes, Samia Ellen Alves Fernandes, Edherlayne Bezerra dos Santos Silva, Jackson Nazareno Gomes de Lima, Anna Karynna Alves de Alencar Rocha, Expedito Silva do Nascimento Junior, Elaine Cristina Gavioli, Edilson Dantas da Silva Junior   +13 more
wiley   +1 more source

Effect of Sertraline in Indomethacin-Induced Gastric Mucosal Damage

, 2012
The antiulcerative effect of sertraline was investigated using an indomethacin-induced ulcer model in rats. After the macroscopic analyses, malondialdehyde and glutathione amounts and superoxide dismutase, glutathione-S-transferase and glutathione ...
Akbas, Ahmet, SAĞLAM, Mustafa, Celebi, Fehmi, Alp, Hamit Hakan, Kisaoglu, Abdullah   +4 more
core   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Antidepressant sertraline and fish behavior

Consumption of antidepressants, including sertraline, increases annually. After their intake and excretion, the residues of pharmaceuticals and their metabolites enter recipients with insufficiently treated wastewater, and they can negatively affect non ...
LEXOVÁ, Veronika
core  

Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids

Translational Psychiatry
In addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs) have multiple other mechanisms that may contribute to clinical effects, and some of these latter actions prompt repurposing of SSRIs for non-psychiatric ...
Yukitoshi Izumi, Angela M. Reiersen, Eric J. Lenze, Steven J. Mennerick, Charles F. Zorumski   +4 more
doaj   +1 more source

Temporal interference stimulation of the nucleus accumbens in obsessive‐compulsive disorder

General Psychiatry, Volume 39, Issue 5, October 2026.
Binxin Huang, Yulong Cheng, Huaiyue Cao, Di Li, Dongdong Shi, Zhen Wang   +5 more
wiley   +1 more source

The Effect of Sertraline on Hemodynamic Parameters and Nitric Oxide Production in Isolated Rat Hearts Subjected to Ischemia and Reperfusion

Journal of Experimental Pharmacology, 2019
Bartosz Grotthus, Adam Szeląg Department of Pharmacology, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Bartosz GrotthusDepartment of Pharmacology, Wroclaw Medical University, Ul. Jana Mikulicza-Radeckiego 2, Wrocław 50-345, PolandTel +48 71
Grotthus B, Szeląg A
doaj  

Involvement of potassium channels in hypoglycemic effect of sertraline

, 2006
120-122Effect of 21 days administration of sertraline (30 mg/kg, po) in streptozotocin (55 mg/kg, ip) induced diabetic and non-diabetic rats produced hypoglycemia in diabetic and non-diabetic rats.
Khanam, Razia, Pillai, K K
core  

Sertraline as an Antidepressant and Inflammatory Cytokines in Depressive Disorders: A Systematic Review and Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. [PDF]

Med Sci (Basel)
Rossetto RF, Pissocaro JS, Cavalheri DA, Raimundo RD, Barbalho SM, Porto AA, Garner DM, Valenti VE.   +7 more
europepmc   +1 more source

Effects of lavender oil preparation silexan on different symptoms of major depression - results from a randomized, controlled trial. [PDF]

Int J Neuropsychopharmacol
Möller HJ, Anghelescu IG, Volz HP, Seifritz E, Schläfke S, Kasper S.   +5 more
europepmc   +1 more source