Results 111 to 120 of about 47,341 (232)

Urinary Incontinence Associated with Sertraline use in a Young SSRI-Naïve Female Patient: a Case Report

Jurnal Psikiatri Surabaya
Introductions: Urinary incontinence is a side effect of several antidepressants, especially those in the SSRI and SNRI groups. Sertraline, a popular SSRI effective against a wide range of mental disorders, is one such drug with a clear association with a
Anna Elissa
doaj   +1 more source

An international survey of the relatives and friends of electroconvulsive therapy recipients

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Objectives This study aimed to address the paucity of studies of the relatives and friends of electroconvulsive therapy (ECT) patients. Methods A total of 1144 people responded to an online survey. Results The respondents included 286 relatives and friends of ECT recipients, from 22 countries.
Christopher Harrop, Sue Cunliffe, Sarah Price Hancock, Lucy Johnstone, Lisa Morrison, John Read   +5 more
wiley   +1 more source

Utilizing RxNorm to Support Practical Computing Applications: Capturing Medication History in Live Electronic Health Records

, 2012
RxNorm was utilized as the basis for direct-capture of medication history data in a live EHR system deployed in a large, multi-state outpatient behavioral healthcare provider in the United States serving over 75,000 distinct patients each year across 130
Bodenreider, Bodenreider, Casey C. Bennett, Cover, Fung, Henkel, Hernandez, Hoffer, Kobayashi, Levin, Nelson, O’Neill, Palchuk, Pathak, Richesson, Ruch, Russell, Shannon, Szegedi, Wade, Zeng   +20 more
core   +1 more source

Association Between Pruritus and Healthcare Utilization and Costs Among Individuals With Primary Biliary Cholangitis

Liver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Background and Aims Pruritus is a debilitating, under‐prioritized symptom of primary biliary cholangitis (PBC). This study assessed its impact on healthcare resource utilization (HCRU) and costs in the US. Methods A retrospective cohort study of individuals with PBC was conducted using Komodo's claims and laboratory data between September 1 ...
Robert G. Gish, Michel H. Mendler, Edward A. Mena, Chong Kim, C. Fiorella Murillo Perez, Yi Pan, Lauren A. Do, Mihail Samnaliev, Maria Agapova   +8 more
wiley   +1 more source

Learning Outcomes That Maximally Differentiate Psychiatric Treatments

International Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives To develop a statistical method that uncovers clinically meaningful differences between active psychiatric treatments, even when traditional rating scales fail to do so. Methods We introduce Supervised Varimax (SV), a novel algorithm that transforms individual items from clinical rating scales into a small set of optimized outcomes ...
Eric V. Strobl, Semmie Kim
wiley   +1 more source

Sertraline and inflammatory markers in major depression: a systematic review and meta-analysis

Annals of General Psychiatry
Background Increasing evidence suggests a link between major depressive disorder (MDD) and inflammatory pathways. Sertraline, a commonly used selective serotonin reuptake inhibitor (SSRI), may influence inflammatory cytokine levels.
ZiLiang Xie, Zheng Gao, Xue Li, Shuo Li, Fan Tang, Caiyi Zhang   +5 more
doaj   +1 more source

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu, Seita Yasuda, Hitoshi Maeshima, Tomoya Ichikawa, Hajime Baba   +4 more
wiley   +1 more source

Glutathione‐Related Metabolite Levels and Enzyme Activities in Depression: A Systematic Review and Meta‐Analysis

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We conducted a systematic review and meta‐analysis to compare the levels of glutathione‐related metabolites. Our meta‐analysis indicated significantly decreased activity of glutathione‐peroxidase in patients with depression compared with healthy controls, while the levels of glutathione and glutathione reductase were not significantly different between
Takahide Etani, Nobuaki Hondo, Sho Moriguchi, Kazunari Yoshida, Sotaro Moriyama, Koki Takahashi, Tahichi Moritake, Yumina Nakamura, Ryoma Kani, Shiori Honda, Masataka Wada, Sakiko Tsugawa, Yukino Mori, Hikari Segawa, Tony Kaku, Hiroyuki Uchida, Shinichiro Nakajima   +16 more
wiley   +1 more source

Comparative Sleep Architecture Profiles of Antidepressants in Mice: Pharmacological Characterization of Paroxetine, Sertraline, Duloxetine, Mirtazapine and Vortioxetine

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study compared five antidepressants (paroxetine, sertraline, duloxetine, mirtazapine, and vortioxetine) in mice using EEG/EMG, revealing distinct effects on REM and NREM sleep. The figure illustrates changes in sleep architecture during the light phase (ZT0–12).
Junya Maruoka, Ryo Egami, Yuto Akita, Kohei Kozuka, Yusuke Kakumoto, Tetsuro Kikuchi, Kazuhiko Kume   +6 more
wiley   +1 more source

The PREDEP-SERT study protocol: A 6-month follow-up cohort study of predictors of effectiveness, tolerability and safety of sertraline for depression using Therapeutic Drug Monitoring.

PLoS ONE
Sertraline is a common first-line pharmacological treatment of Major Depressive Disorder (MDD). There is no established consensus nor clinical guidelines for personalized dose adjustments, which imply risks of toxicity and lack of efficacy.
Patricio Molero, Covadonga Canga-Espina, Begoña Tapia-Alzuguren, José Pablo Bullard, María Del Mar Unceta-González, Enrique Aubá, Jorge M Núñez-Córdoba, Felipe Ortuño, Azucena Aldaz   +8 more
doaj   +1 more source