Results 141 to 150 of about 29,187 (219)

Involvement of potassium channels in hypoglycemic effect of sertraline

, 2006
120-122Effect of 21 days administration of sertraline (30 mg/kg, po) in streptozotocin (55 mg/kg, ip) induced diabetic and non-diabetic rats produced hypoglycemia in diabetic and non-diabetic rats.
Khanam, Razia, Pillai, K K
core  

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi, Alphonse Charbel, Jan Pfeiffenberger, Uta Merle, Jessica Seessle, Theresa Wenz, Christa Flechtenmacher, Patrick Michl, Conrad Rauber   +8 more
wiley   +1 more source

Sertraline Hydrochloride

, 2017
This poster, presented at the Natural Sciences Poster Session at Parkland College, provides the chemical makeup, dosage, and effects of Sertraline Hydrochloride, trade name Zoloft, used to treat the symptoms of depression, obsessive compulsive disorder ...
Fehr, Michelle L.
core  

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Antidepressant sertraline and fish behavior

Consumption of antidepressants, including sertraline, increases annually. After their intake and excretion, the residues of pharmaceuticals and their metabolites enter recipients with insufficiently treated wastewater, and they can negatively affect non ...
LEXOVÁ, Veronika
core  

Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks

Clinical &Experimental Allergy, Volume 56, Issue 7, Page 739-747, July 2026.
In the phase 3 KONFIDENT trial of oral sebetralstat for on‐demand treatment of hereditary angioedema attacks, many attacks induced moderate‐to‐extreme anxiety. Sebetralstat reduced anxiety versus placebo; time to reductions agreed with trial endpoints, such as time to beginning of symptom relief.
Timothy Craig, Emel Aygören‐Pürsün, Jonathan A. Bernstein, Paula J. Busse, Teresa Caballero, Danny M. Cohn, Mar Guilarte, Henriette Farkas, Douglas H. Jones, Sorena Kiani‐Alikhan, Michael E. Manning, Marcus Maurer, Marc A. Riedl, Sinisa Savic, H. James Wedner, Patrick F. K. Yong, Andrea Zanichelli, Sally van Kooten, Matthew Iverson, Erik Hansen, James Hao, Michael D. Smith, Christopher M. Yea, Paul K. Audhya, William R. Lumry   +24 more
wiley   +1 more source

Effect of Sertraline in Indomethacin-Induced Gastric Mucosal Damage

, 2012
The antiulcerative effect of sertraline was investigated using an indomethacin-induced ulcer model in rats. After the macroscopic analyses, malondialdehyde and glutathione amounts and superoxide dismutase, glutathione-S-transferase and glutathione ...
Akbas, Ahmet, SAĞLAM, Mustafa, Celebi, Fehmi, Alp, Hamit Hakan, Kisaoglu, Abdullah   +4 more
core   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids

Translational Psychiatry
In addition to modulating serotonin transport, selective serotonin reuptake inhibitors (SSRIs) have multiple other mechanisms that may contribute to clinical effects, and some of these latter actions prompt repurposing of SSRIs for non-psychiatric ...
Yukitoshi Izumi, Angela M. Reiersen, Eric J. Lenze, Steven J. Mennerick, Charles F. Zorumski   +4 more
doaj   +1 more source

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt, Michael Farrell, Michael Doyle, Jack Stone, Chrianna Bharat, Matt Hickman, Marianne Martinello, Don Weatherburn, Kimberlie Dean, Joe Coyte, Christel Macdonald, Mary Ellen Harrod, Luke Grant, Gloria Larman, Peter Vickerman, Colette McGrath, Peter Thompson, Alison Churchill, Greg Dore, Thomas Santo Jr   +19 more
wiley   +1 more source