Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms
British Journal of Clinical Pharmacology, EarlyView.Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola +8 more
wiley +1 more source
Molecular Psychiatry, 2019 Medications to treat major depressive disorder (MDD) are not equally effective across patients. Given that neural response to rewards is altered in MDD and given that reward-related circuitry is modulated by dopamine and serotonin, we examined, for the ...
T. Greenberg +20 more
semanticscholar +1 more source
MedicinaBackground and Objectives: Sertraline is a selective serotonin reuptake inhibitor (SSRI) that is frequently prescribed during pregnancy to treat mood disorders.
Ayman A. Refai +8 more
doaj +1 more source
Treatment with high-dose antidepressants severely exacerbates the pathological outcome of experimental Escherichia coli infections in poultry. [PDF]
PLoS ONE, 2017 There is an urgent need for novel antibiotics as the current antibiotics are losing their value due to increased resistance among clinically important bacteria. Sertraline, an on-marked anti-depressive drug, has been shown to modify bacterial activity in
Sofie Kromann +7 more
doaj +1 more source
Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]
, 2002 Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph +4 more
core +1 more source
Psychoactive prescription drug use and misuse in patients on opioid agonist treatment
British Journal of Clinical Pharmacology, EarlyView.Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro +5 more
wiley +1 more source
Iranian South Medical Journal, 2020 Background: Sertraline, along with its beneficial antidepressant effects, may have adverse effects on the fertility and reproductive system. In recent years, the negative effects of sertraline on body tissues have been shown to some extent.
Hassan Morovvati +7 more
doaj
Cost-effectiveness analysis of pharmaceutical treatment options in the first-line management of major depressive disorder in Belgium [PDF]
, 2014 The objective of this study was to assess the cost effectiveness of commonly used antidepressants as first-line treatment of major depressive disorder (MDD) in Belgium.
Annemans, Lieven +5 more
core +2 more sources
Clinical pharmacology consultations and their implementation in clinical decision making
British Journal of Clinical Pharmacology, EarlyView.Aims One of the key roles of clinical pharmacologists is to work as consultants for other medical specialties. We wanted to investigate the characteristics of clinical pharmacology consultations, compare the types of consultations from different specialties, and evaluate how well the recommendations given were followed.
Mirjam Kauppila +2 more
wiley +1 more source
Sertraline use in pregnancy and placental transfer: A pharmacokinetic prospective cohort study
PregnancyIntroduction Depression in pregnancy is common and the use of antidepressants in pregnancy, especially sertraline, is on the rise. Although sertraline is known to cross the placenta, the level of transfer to the foetus is unclear.
Charlotte Goutallier +8 more
doaj +1 more source