Results 41 to 50 of about 31,475 (230)

Histological and Histometrical Study of Prostate Following Administration of Sertraline in Adult Mice

Iranian South Medical Journal, 2020
Background: Sertraline, along with its beneficial antidepressant effects, may have adverse effects on the fertility and reproductive system. In recent years, the negative effects of sertraline on body tissues have been shown to some extent.
Hassan Morovvati, Mohammadkazem Koohi, Zabihollah Khaksar, Freshteh Morshedi, Hojat Anbara, Fatemeh Parsaei, Mehdi Hadijafari, Hamidreza Moradi   +7 more
doaj  

Treatment with high-dose antidepressants severely exacerbates the pathological outcome of experimental Escherichia coli infections in poultry. [PDF]

PLoS ONE, 2017
There is an urgent need for novel antibiotics as the current antibiotics are losing their value due to increased resistance among clinically important bacteria. Sertraline, an on-marked anti-depressive drug, has been shown to modify bacterial activity in
Sofie Kromann, Egle Kudirkiene, Lili Li, Ida Thoefner, Elisabeth Daldorph, Jens Peter Christensen, Hecheng Meng, Rikke Heidemann Olsen   +7 more
doaj   +1 more source

The Preparation and Intra- and Intermolecular Addition Reactions of Acyclic N-Acylimines:  Application to the Synthesis of (±)-Sertraline

, 2016
Intramolecular endo-cyclization reactions of N-acyliminium ions have seen wide application for the synthesis of heterocyclic compounds. The corresponding exocyclic variant, which would provide 1-aminotetralin derivatives, for example, has little ...
Michael P. DeNinno (244221), John B. Etienne (3016290), Cynthia Eller (3016275)   +2 more
core   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

British Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi, Valentina Giunchi, Michael Thiede, Elisa Sangiorgi, Marco Menchetti, Elisabetta Poluzzi   +5 more
wiley   +1 more source

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source

PTSD Symptom Reduction with Ketamine Therapy Compared with Traditional Sertraline Therapy: A Systematic Review [paper] [PDF]

The present study sought to investigate evidence for the use of ketamine in comparison to sertraline for symptom remission in adults with Post-Traumatic Stress Disorder.
Timmons, Melissa
core   +1 more source

Sertraline use in pregnancy and placental transfer: A pharmacokinetic prospective cohort study

Pregnancy
Introduction Depression in pregnancy is common and the use of antidepressants in pregnancy, especially sertraline, is on the rise. Although sertraline is known to cross the placenta, the level of transfer to the foetus is unclear.
Charlotte Goutallier, Stephen Tong, Cassius Phogole, Tracy Kellermann, Manarangi De Silva, Eric Decloedt, Catherine A Cluver, Roxanne Hastie, Anthea Lindquist   +8 more
doaj   +1 more source

Sertraline in the treatment of mixed anxiety and depression disorder

, 2000
Background: Mixed anxiety and depression disorder (MAD) has been recognized in ICD-10 as a diagnostic group including those anxious and depressed patients which do not fit sufficient criteria for any major axis I disorders.
Carrasco Perera, José Luis, Díaz Marsa, Marina Francisca, Sáiz Ruiz, Jerónimo   +2 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

A UHPLC METHOD FOR SERTRALINE DETERMINATION [PDF]

, 2017
Purpose: To develop and implement a UHPLC method for quantitative determination of sertraline in biological samples – mostly human blood and urine. Material&Methods: Blood and urine samples available from Laboratory of analytical toxicology and Clinic ...
Georgi Bonchev, Petko Marinov, Ivaylo Vazharov, Marieta Yovcheva, Snezha Zlateva   +4 more
core   +1 more source