Results 21 to 30 of about 31,475 (230)

PoPK of sertraline

, 2022
Population pharmacokinetic of Sertraline (control files)
Milan Stoiljkovic (12957836), Slobodan M. Janković (12957857), Jasmina Milovanovic (12957860), Valentina Nikolic (12957859)   +3 more
core   +1 more source

Effect of sertraline as an add-on therapy in T2DM patients with comorbid depression: An open label randomized controlled trial

Indian Journal of Endocrinology and Metabolism, 2019
Objectives: To study the effect of sertraline on depression in type 2 diabetes mellitus (T2DM) patients with comorbid depression. Materials and Methods: An open label randomized control study.
Padala R Kumar, Anindita Chatterjee, Jayanti P Behera, Sudhiranjan Patnaik   +3 more
doaj   +1 more source

The effect of zopiclone co-administration on sertraline initial dosage optimization in pediatric major depressive disorder patients based on model-informed precision dosing

Frontiers in Pharmacology
ObjectiveThe present study aims to explore the initial dosage optimization of sertraline in pediatric major depressive disorder (MDD) patients based on model-informed precision dosing (MIPD).MethodsA total of 111 pediatric MDD patients treated with ...
Xiao Chen, Ke Hu, Hao-Zhe Shi, Su-Mei He, Yang Yang, Chao-Wen Yang, Yue Zhang, Xue Tian, Ye Li, Yu-Hang Gao, Wen-Yi Xu, Cun Zhang, Dong-Dong Wang   +12 more
doaj   +1 more source

Catalytic Asymmetric Synthesis of Diarylacetates and 4,4-Diarylbutanoates. A Formal Asymmetric Synthesis of (+)-Sertraline

, 2016
The intermolecular C−H insertion chemistry of phenyldiazoacetates catalyzed by dirhodium tetrakis((S)-N-(dodecylbenzenesulfonyl)prolinate) (Rh2(S-DOSP)4) can be effectively carried out on cyclohexadienes, leading to the asymmetric synthesis of ...
Douglas G. Stafford (1336788), Huw M. L. Davies (1336170), Tore Hansen (2078749)   +2 more
core   +1 more source

Machine learning-based prediction of sertraline concentration in patients with depression through therapeutic drug monitoring

Frontiers in Pharmacology
Background: Sertraline is a commonly employed antidepressant in clinical practice. In order to control the plasma concentration of sertraline within the therapeutic window to achieve the best effect and avoid adverse reactions, a personalized model to ...
Ran Fu, Ran Fu, Xin Hao, Jing Yu, Jing Yu, Donghan Wang, Donghan Wang, Jinyuan Zhang, Ze Yu, Fei Gao, Chunhua Zhou, Chunhua Zhou   +11 more
doaj   +1 more source

Sertraline for Functional Recovery After Acute Ischemic Stroke: A Prospective Observational Study

Frontiers in Neurology, 2021
Background: Neuroprotective and neurorestorative effects have been postulated for selective serotonin-reuptake inhibitors (SSRI). We hypothesized that sertraline, which is characterized by less severe adverse effects and more stable pharmacokinetics than
Isabella Stuckart, Timo Siepmann, Christian Hartmann, Lars-Peder Pallesen, Annahita Sedghi, Jessica Barlinn, Heinz Reichmann, Volker Puetz, Kristian Barlinn   +8 more
doaj   +1 more source

Sertraline for HIV-associated cryptococcal meningitis [PDF]

, 2016
Joshua Rhein and colleagues1 used measurements of sertraline plasma concentrations and the minimum inhibitory concentrations (MICs) for sertraline to determine the probability of achieving therapeutic sertraline concentrations in the brains of patients ...
Alffenaar, Jan-Willem C., Day, Jeremy N, van der Elst, KC, Thwaites, Guy, Veringa, A, Thwaites, Guy E., van der Elst, Kim C. M., Alffenaar, JW, Veringa, Anette, Day, Jeremy N.   +9 more
core   +1 more source

Population pharmacokinetic approach to guide personalized sertraline treatment in Chinese patients

Heliyon
Object: Sertraline is a first-line SSRI for the treatment of depression and has the same effectiveness along with a superior safety profile compared to other medications.
Zi Zhang, Zhihao Guo, Yaqian Tan, Lu Li, Zhanzhang Wang, Yuguan Wen, Shanqing Huang, Dewei Shang   +7 more
doaj   +1 more source

Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

Neurobiology of Disease, 2008
Huntington's disease (HD) is an inherited progressive neurodegenerative disorder resulting from CAG repeat expansion in the gene that encodes for the protein huntingtin.
Wenzhen Duan, Qi Peng, Naoki Masuda, Eric Ford, Erik Tryggestad, Bruce Ladenheim, Ming Zhao, Jean Lud Cadet, John Wong, Christopher A. Ross   +9 more
doaj   +1 more source

Sertraline-Induced Tics: A Case Report and Narrative Review.

, 2022
This brief report describes the case of a 16-year-old girl who was commenced on sertraline for anxiety and depression, and subsequently developed severe and debilitating motor tics.
Semran Badeshae (23521318), Yulia Furlong (23283574), Ramesh Arasu (23521315), Wai Chen (23290849)   +3 more
core