Results 31 to 40 of about 47,341 (232)

The effect of zopiclone co-administration on sertraline initial dosage optimization in pediatric major depressive disorder patients based on model-informed precision dosing

Frontiers in Pharmacology
ObjectiveThe present study aims to explore the initial dosage optimization of sertraline in pediatric major depressive disorder (MDD) patients based on model-informed precision dosing (MIPD).MethodsA total of 111 pediatric MDD patients treated with ...
Xiao Chen, Ke Hu, Hao-Zhe Shi, Su-Mei He, Yang Yang, Chao-Wen Yang, Yue Zhang, Xue Tian, Ye Li, Yu-Hang Gao, Wen-Yi Xu, Cun Zhang, Dong-Dong Wang   +12 more
doaj   +1 more source

Effect of sertraline as an add-on therapy in T2DM patients with comorbid depression: An open label randomized controlled trial

Indian Journal of Endocrinology and Metabolism, 2019
Objectives: To study the effect of sertraline on depression in type 2 diabetes mellitus (T2DM) patients with comorbid depression. Materials and Methods: An open label randomized control study.
Padala R Kumar, Anindita Chatterjee, Jayanti P Behera, Sudhiranjan Patnaik   +3 more
doaj   +1 more source

Nutraceutical-based integrative medicine: adopting a mediterranean diet pyramid for attaining healthy ageing in veterans with disabilities [PDF]

, 2018
Veterans with disability represent a big burden worldwide and often require long-term rehabilitation. Unhealthy dietary and lifestyle habits, including smoke and alcohol abuse, are common in veterans.
Aiello, Paola, Buccolieri, Cosimo, Catasta, Giovina, Ciccotti, Mario, Lista, Florigio, Palmery, Maura, Peluso, Ilaria, Raguzzini, Anna, Reggi, Raffaella, Sciarra, Tommaso   +9 more
core   +1 more source

Population pharmacokinetic approach to guide personalized sertraline treatment in Chinese patients

Heliyon
Object: Sertraline is a first-line SSRI for the treatment of depression and has the same effectiveness along with a superior safety profile compared to other medications.
Zi Zhang, Zhihao Guo, Yaqian Tan, Lu Li, Zhanzhang Wang, Yuguan Wen, Shanqing Huang, Dewei Shang   +7 more
doaj   +1 more source

Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. [PDF]

, 2018
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these ...
Barsoum, Amir, Benkelfat, Chawki, Berney, Alexandre, Cottraux, Jean, Diksic, Mirko, Gravel, Paul, Leyton, Marco, Lissemore, Jennifer I, Nordahl, Thomas E, Pinard, Gilbert, Sibon, Igor, Sookman, Debbie   +11 more
core   +2 more sources

Machine learning-based prediction of sertraline concentration in patients with depression through therapeutic drug monitoring

Frontiers in Pharmacology
Background: Sertraline is a commonly employed antidepressant in clinical practice. In order to control the plasma concentration of sertraline within the therapeutic window to achieve the best effect and avoid adverse reactions, a personalized model to ...
Ran Fu, Ran Fu, Xin Hao, Jing Yu, Jing Yu, Donghan Wang, Donghan Wang, Jinyuan Zhang, Ze Yu, Fei Gao, Chunhua Zhou, Chunhua Zhou   +11 more
doaj   +1 more source

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]

, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae, Chianu, Marin, Mihalachi-Anghel, Maria, Podgurschi, Lilia, Pogonea, Ina, Socea, Bogdan, Ștefănescu, Emil   +6 more
core   +2 more sources

Granisetron-mediated augmentation of sertraline therapeutic effect in obsessive-compulsive disorder: a double-blind placebo-controlled, randomized clinical trial

BMC Pharmacology and Toxicology, 2022
Background Medications currently recommended for the treatment of Obsessive-Compulsive Disorder (OCD) usually relieve the severity of symptoms by as much as 20–30%, and satisfactory treatment is obtained in 40–60% of patients with OCD.
Ala Ghobadian, Saba Mokhtari, Behnam Shariati, Leila Kamalzadeh, Mohsen Shati, Mehrdad Eftekhar Ardebili, Masoomeh Yarahmadi, Mohammadreza Shalbafan   +7 more
doaj   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source