Results 71 to 80 of about 52,947 (295)

Bilateral cystoid macular edema misdiagnosed as pars planitis in a patient on sertraline therapy

American Journal of Ophthalmology Case Reports, 2018
Purpose: To describe the presentation, clinical course and management of a patient with bilateral maculopathy associated with sertraline. Observations: We report a rare case of bilateral cystoid macular edema and subretinal fluid in a 78-year-old Asian ...
Aniruddha Agarwal, Kanika Aggarwal, Aman Kumar, Vishali Gupta   +3 more
doaj   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy

JCI Insight, 2018
Lung cancer patients treated with tyrosine kinase inhibitors (TKIs) often develop resistance. More effective and safe therapeutic agents are urgently needed to overcome TKI resistance.
Xingwu Jiang, Weiqiang Lu, Xiaoyang Shen, Quan Wang, Jing Lv, Mingyao Liu, F. Cheng, Zhongming Zhao, Xiufeng Pang   +8 more
semanticscholar   +1 more source

Exercise for depression [PDF]

, 2009
Background Depression is a common and important cause of morbidity and mortality worldwide. Depression is commonly treated with antidepressants and/or psychotherapy, but some people may prefer alternative approaches such as exercise.
Antonelli, Armstrong, Armstrong, Astin, Auchus, Babyak, Bartholomew JB Morrison, Beesley, Berlin, Berlin, Biddle, Biddle, Blue, Blumenthal, Blumenthal, Bodin, Bonnet, Bosscher, Boyll, Broocks, Brown, Buffone, Burbach, Byrne, Carlson, Carney, Chou, Cohen, Conroy, Coppenolle, Cotman, Coverley Veale, Craft, D'Amato, Dalton, DerSimonian, DeVaney, DiLorenzo, Dimeo, Dishman, Doyne, Doyne, Duclos, Dunn, Dunn, Dunn AL Trivedi MH Kampert JB Clark CG Chambliss, Eby, Emery, Emery, Epstein, Ernst, Fetsch, Fetsch, Fitzsimmons, Fremont, Giardinelli, Glenister, Goodwin, Greist, Hales, Hannaford, Hartz, Hayward, Hembree, Herrera, Hess-Homeier, Hughes, Kaplan, Khatri, Kim, Kitzman, Klein, Knapen, Knuppen, Krogh, Kubesch, Kupecz, Kurz, Labbe, Lacombe, LaFontaine, Lai, Lawlor, LePore, Leppamaki, Margolis, Martinsen, Martinsen, Martinsen, Martinsen, Martinsen, Martinsen, Martinsen, Martinsen, Mather, McCann, McNeil, Merwe, Moncrieff, Moore, Moreau, Morey, Motl, Moussavi, Munro, Nabkasorn, Neidig, Netz, Nguyen, North, Orth, Ouyang, Palleschi, Palmer, Pappas, Passmore, Pelham, Penninx, Perri II, Pezzarossa, Pinchasov, Plante, Raglin, Reuter, Rhodes, Rief, Rosenthal, Roth, Roth, Sachs, Sachs, Salminen, Salmon, Salmon, Sanstead, Schulz, Scully, Setaro, Sexton, Simons, Singh, Singh, Singh, Sjosten, Skrinar, Sonstroem, Sorensen, Stathopoulou, Stein, Stein, Stern, Stewart, Taylor, Tenorio, Trivedi, Tsang, Tsang, Veale, Veale, Vickers, Vliet, Weinstein, Weiss, Weyerer, Wieman, Williams, Williams, Williams   +167 more
core   +3 more sources

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

A Randomized Placebo-Controlled Trial of Omega-3 and Sertraline in Depressed Patients With or at Risk for Coronary Heart Disease.

Journal of Clinical Psychiatry, 2019
OBJECTIVE Studies of depressed psychiatric patients have suggested that antidepressant efficacy can be increased by adding eicosapentaenoic acid (EPA), one of the omega-3 fatty acids found in fish oils.
R. Carney, K. Freedland, E. Rubin, M. Rich, Brian C. Steinmeyer, W. Harris   +5 more
semanticscholar   +1 more source

Sertraline demonstrates fungicidal activity in vitro for Coccidioides immitis

Mycology, 2016
Coccidioidomycosis causes substantial morbidity in endemic areas. Disseminated coccidioidomycosis is an AIDS defining condition and treatment often requires lifelong antifungal therapy.
Simon Paul, Roger B. Mortimer, Marilyn Mitchell   +2 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Sertraline reduces IL-1β and TNF-α mRNA expression and overcomes their rise induced by seizures in the rat hippocampus.

PLoS ONE, 2014
We recently discovered that the antidepressant sertraline is an effective inhibitor of hippocampus presynaptic Na+ channel permeability in vitro and of tonic-clonic seizures in animals in vivo. Several studies indicate that the pro-inflammatory cytokines
María Sitges, Carlos D Gómez, Blanca I Aldana   +2 more
doaj   +1 more source

Self-limiting diarrhea in an infant exposed to sertraline in breast milk

Journal of Family Medicine and Primary Care, 2017
Sertraline is widely used to treat postpartum depression. Though studies found detectable levels of sertraline in infant blood, very few adverse effects are reported.
N A Uvais
doaj   +1 more source