Results 121 to 130 of about 730,822 (283)

Commercial serum-free media: hybridoma growth and monoclonal antibody production.

, 1991
Various growth factors, hormones and proteins present in serum are presumed to be responsible for its growth-stimulating activity in culture media.
FACCHINI A., MARIANI A.R., LALLI E., MONACO M.C., VITALE, Marco, MARIANI E.   +5 more
core  

Ex vivo expansion of human T cells for adoptive immunotherapy using the novel Xeno-free CTS Immune Cell Serum Replacement

, 2015
The manufacture of clinical grade cellular products for adoptive immunotherapy requires ex vivo culture and expansion of human T cells. One of the key components in manufacturing of T cell therapies is human serum (HS) or fetal bovine serum (FBS), which ...
Schjetne, Karoline W., Lee, Sau K., Smith, Corey, Rehan, Sweera, Beagley, Leone, Aarvak, Tanja, Khanna, Rajiv, Okern, Grethe   +7 more
core   +1 more source

Bladder organoid conditioned media enhances myoblast proliferation under serum free conditions

Scientific Reports
In recent years, the growing attention to sustainable food production and animal welfare has positioned cultured meat technologies. A key technical requirement for implementing this approach is the development of culture media independent of fetal bovine
Yuko Nagashima, Haru Yamamoto, Mohamed Elbadawy, Yoshiko Naito, Amira Abugomaa, Masahiro Kaneda, Tatsuya Usui, Kazuaki Sasaki   +7 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Cultures Through Time: Forging a Xeno-Free Future for Cell Culture-Based Virology

Vaccines
As a cornerstone of modern science, cell lines are the foundational platforms for key medical advances. They enable vaccinology (through viral propagation and attenuation), gene therapy (via vector development), and biopharmaceutical production (via ...
Arvind Singh Kaulsay, Nurshariza Abdullah, Nur Amelia Azreen Adnan   +2 more
doaj   +1 more source

Multi-objective Bayesian algorithm automatically discovers low-cost high-growth serum-free media for cellular agriculture application. [PDF]

Eng Life Sci, 2023
Cosenza Z, Block DE, Baar K, Chen X.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics. [PDF]

Cell Mol Bioeng, 2022
Cui Y, Nash AM, Castillo B, Sanchez Solis LD, Aghlara-Fotovat S, Levitan M, Kim B, Diehl M, Veiseh O.   +8 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Grade 12 teachers' attitude towards mass-media transmitted educational supplements [PDF]

, 2000
ThesisThe purpose of this research was to investigate the essence of Grade 12 teachers' attitude towards the use of Mass-Media Educational Supplements, to textbooks and teachers as well.
Mokgatlhe, Phefo L.
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