Advanced Healthcare Materials, EarlyView.An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
Integrated evaluation of immune response, inflammatory biomarkers, clinical features and hemato-biochemical changes in bovine ephemeral fever-affected cattle. [PDF]
Ir Vet JAbdel-Hamied E +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source
Characterization of a Bovine Serum Albumin-Derived Pro-Cognitive Peptide (bSAPP): An Orally Active Peptide Alleviates Cognitive Decline in HFD-Fed Mice via CCK Signaling Through the Gut-Brain Axis. [PDF]
FASEB JZhang B +5 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez +4 more
wiley +1 more source
Glucose modulates macrophage polarization via glycating adsorbed albumin on titanium. [PDF]
Mater Today BioJiang S, Meng J, Wang Q, Zou Y, Mou Y.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Exploring ethical, sustainable and effective foetal bovine serum alternatives for <i>in vitro</i> mammalian cell culture. [PDF]
Front ToxicolMeng H, Day PJR.
europepmc +1 more source
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Synthesis of BSA-Coated Iron Oxide Nanoparticles with Size Control for High-Performance <i>T</i><sub>1</sub> Contrast Agents in Magnetic Resonance Imaging. [PDF]
BiomoleculesKolawole B, Zheng J, Cao D, Zhao Y.
europepmc +1 more source