Results 61 to 70 of about 877,460 (349)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Stimulated low-frequency Raman scattering in albumin [PDF]

Journal of Russian Laser Research, Volume 40, Number 1, January, 2019, 2019
Stimulated low-frequency Raman scattering can give essential information about the elastic properties of different nanoparticles systems, in particular, biological nanostructures. In the present study, low-frequency vibrational modes in human and bovine serum albumin were for the first time investigated using stimulated low-frequency Raman scattering ...
arxiv   +1 more source

An oligofluorene truxene based distributed feedback laser for biosensing applications [PDF]

, 2014
The first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported.
Al-Hakim, Alexander L Kanibolotsky, Anne-Marie Haughey, Armani, Attie, Benoit Guilhabert, DeVos, Dííaz-García, Erol, Foucher, Ge, Glenn A Burley, Green, Guilhabert, Haughey, Herrnsdorf, Hirsch, Jenison, Kanibolotsky, Kim, Lu, Lu, Martin D Dawson, Nicolas Laurand, Peter J Skabara, Ramsden, Ruiz-Taylor, Scullion, Tan, Tsiminis, Vollmer, Williams, Wong, Yang   +33 more
core   +1 more source

Recent Advancements in Serum Albumin-Based Nanovehicles Toward Potential Cancer Diagnosis and Therapy

Frontiers in Chemistry, 2021
Recently, drug delivery vehicles based on nanotechnology have significantly attracted the attention of researchers in the field of nanomedicine since they can achieve ideal drug release and biodistribution.
Xue Shen, Xiyang Liu, Tingting Li, Yin Chen, Yang Chen, Pan Wang, Lin Zheng, Hong Yang, Chunhui Wu, Shengqi Deng, Yiyao Liu   +10 more
semanticscholar   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Synthetic tumor-associated glycopeptide antigens. [PDF]

, 1990
Glycopeptides with TN antigen (GalNAc)Ser/Thr and T-antigen structures (beta Gall-3GalNAc)Ser/Thr, described as tumor-associated antigens, were synthesized and coupled to bovine serum albumin. Alternatively, synthetic methods for the construction of beta-
Birnbach, S, Kunz, H, Lang, U, März, J, Schilling, M, Unverzagt, C, Waldmann, H, Wernig, P   +7 more
core   +2 more sources

Adsorption Of Bovine Serum Albumin On Ceo2

, 2014
Preparation of nanoparticles of cerium oxide and adsorption of bovine serum albumin on them were studied. Particle size distribution and influence of pH on zeta potential of prepared CeO2 were determined. Average size of prepared cerium oxide nanoparticles was 9 nm. The simultaneous measurements of the bovine serum albumin adsorption and zeta potential
openaire   +8 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Quantitative studies on the interaction of concanavalin A, the carbohydrate-binding protein of the jack bean, with model carbohydrate-protein conjugates [PDF]

, 1973
The interaction of concanavalin A with a comprehensive series of carbohydrate-bovine serum albumin comjugates was investigated by agar gel diffusion and quantitative precipitation techniques.
Agrawal, Allen, Arakatsu, Avery, Babers, Beiser, Boas, Cifonelli, Conchie, Easty, Elson, Gelewitz, Gleich, Goebel, Goldstein, Goldstein, Goldstein, Goldstein, Goldstein, Goldstein, Gould, Harrack, Heidelberger, Hissins, I.J. Goldstein, Inbar, Iyer, Iyer, Kabat, Kabat, Karush, Landsteiner, Manners, Novogrodsky, Pauling, Pauling, Pauling, Pauling, Pepe, Poretz, Poretz, Poretz, Powell, R.N. Iyer, Robinson, Scott, Singer, Smith, So, So, So, So, So, Summer, Weckster, Westphal, Yariv   +56 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source