Results 51 to 60 of about 492,888 (308)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Modelling bovine serum albumin inside carbon nanotubes
, 2013 Bovine serum albumin is commonly used in many biochemical applications due to its stability, lack of interference within biochemical reactions and low production cost. Here, we model the interaction of bovine serum albumin inside a carbon nanotube.
Ngamta Thamwattana (19588597) +2 more
core +2 more sources
Adsorption Science & Technology, 2017 Hydroxyapatite is a compound that belongs to the group of apatite minerals. It is a very interesting adsorbent and the main inorganic component of bones and teeth. Hydroxyapatite was obtained using three different methods.
Ewa Skwarek +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Bovine serum albumin interactions with metal complexes [PDF]
Medicine and Pharmacy Reports, 2014 The continuous search for new molecules with therapeutic abilities has led to the synthesis and characterization of a large number of metal complexes, proven to exhibit potential as pharmacological agents through their antibacterial, antiviral, antifungal and antineoplastic properties.
TOPALĂ, TAMARA +3 more
openaire +2 more sources
Electrokinetic study of bovine serum albumin in aqueous solution: Electroviscosity
, 2020 The electrokinetic of bovine serum albumin (BSA) in water is scarcely studied, and the experimental measurements are narrowly reported. Intrinsic viscosity data are very useful in assessing the interaction between the solute and solvent.
Masuelli, Martin Alberto +2 more
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
MoleculesNowadays, several processes to enrich desired bioactive compounds in plant extracts have been developed. The objective of the present study was to assess the performance of bovine serum albumin in increasing the extractive yields of anthraquinones and ...
Chiara Collevecchio +4 more
doaj +1 more source
On the aggregation of bovine serum albumin [PDF]
, 2022 In an attempt to elucidate the aggregation behaviour of bovine serum albumin and its modulation by salt ions, size-exclusion high-performance liquid chromatography was used and complemented by dynamic light scattering.
Rocha, Inês L. D. +4 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source